2. MAPK/ERK Pathway NF-κB
  3. p38 MAPK NF-κB
  4. JX10

JX10 is a senomorphic agent. JX10 suppresses the expression of p38 MAPK and NF-κB. JX10 exhibits competent antiaging effects in C. elegans, senescent cells, and aged mice.

For research use only. We do not sell to patients.

JX10 Chemical Structure

JX10 Chemical Structure

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JX10 Related Antibodies

Top Publications Citing Use of Products

View All p38 MAPK Isoform Specific Products:

View All Isoforms
p38 MAPK p38α p38β MAPK13 p38δ p38γ

View All NF-κB Isoform Specific Products:

View All Isoforms
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

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Description

JX10 is a senomorphic agent. JX10 suppresses the expression of p38 MAPK and NF-κB. JX10 exhibits competent antiaging effects in C. elegans, senescent cells, and aged mice[1].

Molecular Weight

421.51

Formula

C25H28FN3O2
SMILES

FC1=C(C=C(C2=C1)N(C(C3=CC=C(C=C3)OC)=CC2=O)C4CC4)N5CCN(CC5)CC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JX10 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JX10JX 10JX-10p38 MAPKNF-κBNuclear factor-κBNuclear factor-kappaBC. elegansaged miceInhibitorinhibitorinhibit

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