2. Apoptosis MAPK/ERK Pathway PI3K/Akt/mTOR NF-κB Stem Cell/Wnt Neuronal Signaling Epigenetics
  3. Apoptosis p38 MAPK Akt NF-κB Notch Bcl-2 Family MDM-2/p53 Epigenetic Reader Domain
  4. Hexamethylene bisacetamide (Standard)

Hexamethylene bisacetamide (Standard) 

Cat. No.: HY-124284R Purity: ≥98%
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Hexamethylene bisacetamide (Standard) is the analytical standard of Hexamethylene bisacetamide. This product is intended for research and analytical applications. Hexamethylene bisacetamide (HMBA) is a differentiation inducer and selective bromine domain inhibitor that can differentiate across the blood-brain barrier. Hexamethylene bisacetamide can induce tumor cell differentiation and inhibit cell proliferation, showing antitumor activity. Hexamethylene bisacetamide induces apoptosis by Notch1, Bcl-2 and p53 signaling pathways. In addition, Hexamethylene bisacetamide improves the obesity phenotype of mice.

For research use only. We do not sell to patients.

Hexamethylene bisacetamide (Standard) Chemical Structure

Hexamethylene bisacetamide (Standard) Chemical Structure

CAS No. : 3073-59-4

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Hexamethylene bisacetamide (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hexamethylene bisacetamide (Standard)3073-59-4Apoptosisp38 MAPKAktNF-κBNotchBcl-2 FamilyMDM-2/p53Epigenetic Reader DomainPKBProtein kinase BNuclear factor-κBNuclear factor-kappaBDifferentiation inducerSelective bromine domain inhibitorDIO modelSHG-44 cellsA549 cellsMolt4 cellsInhibitorinhibitorinhibit

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