2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. IAXO-101 iodide

IAXO-101 (iodide) is a TLR4/CD14 blocker. IAXO-101 (iodide) can inhibit the innate immune pathway of CD14. IAXO-101 (iodide) is capable of improving the recording performance of intracortical microelectrodes in mice. IAXO-101 (iodide) can also partially alleviate fetal growth restriction, placental vascular damage, and reduce the level of the inflammatory factor TNF-α in pregnant mice infected with malaria. IAXO-101 (iodide) can be used in the research of gestational malaria and inflammatory diseases.

For research use only. We do not sell to patients.

IAXO-101 iodide

IAXO-101 iodide Chemical Structure

CAS No. : 1202388-64-4

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

IAXO-101 iodide Related Antibodies

Top Publications Citing Use of Products

View All Toll-like Receptor (TLR) Isoform Specific Products:

View All Isoforms
TLR3 TLR8 TLR9 TLR2 TLR4 TLR7 TLR1 TLR6

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

IAXO-101 (iodide) is a TLR4/CD14 blocker. IAXO-101 (iodide) can inhibit the innate immune pathway of CD14. IAXO-101 (iodide) is capable of improving the recording performance of intracortical microelectrodes in mice. IAXO-101 (iodide) can also partially alleviate fetal growth restriction, placental vascular damage, and reduce the level of the inflammatory factor TNF-α in pregnant mice infected with malaria. IAXO-101 (iodide) can be used in the research of gestational malaria and inflammatory diseases[1][2].

IC50 & Target[2]

TLR4

 

Molecular Weight

810.02

Formula

C42H84INO5
CAS No.
SMILES

CCCCCCCCCCCCCCO[C@@H]1[C@H]([C@@H]([C@@H](C[N+](C)(C2CCCC2)C)O[C@@H]1OC)O)OCCCCCCCCCCCCCC.[I-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

IAXO-101 iodide Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IAXO-1011202388-64-4IAXO101IAXO 101Toll-like Receptor (TLR)TLR4CD14innate immune pathwaymalariainflammatory diseasesInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
IAXO-101 iodide
Cat. No.:
HY-129684
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.