2. Antibody-drug Conjugate/ADC Related Protein Tyrosine Kinase/RTK
  3. Peptide-Drug Conjugates (PDCs) Ephrin Receptor
  4. (123B9)2-L2-PTX

(123B9)2-L2-PTX is an EphA2-agonistic peptide-drug conjugate (PDC). (123B9)2-L2-PTX consists of a dimeric 123B9 (HY-P10579) and Paclitaxel (HY-B0015). (123B9)2-L2-PTX significantly reduces circulating tumor cells and inhibits lung tumor metastasis in breast-cancer-Metastasis mice model. (123B9)2-L2-PTX can be used for cancers research, such as melanomas and ovarian and breast cancers.

For research use only. We do not sell to patients.

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(123B9)2-L2-PTX Chemical Structure

(123B9)2-L2-PTX Chemical Structure

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(123B9)2-L2-PTX Related Antibodies

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Description

(123B9)2-L2-PTX is an EphA2-agonistic peptide-drug conjugate (PDC). (123B9)2-L2-PTX consists of a dimeric 123B9 (HY-P10579) and Paclitaxel (HY-B0015). (123B9)2-L2-PTX significantly reduces circulating tumor cells and inhibits lung tumor metastasis in breast-cancer-Metastasis mice model. (123B9)2-L2-PTX can be used for cancers research, such as melanomas and ovarian and breast cancers[1].

IC50 & Target

EPHA2

 

Molecular Weight

4155.16

Formula

C192H254Cl2F2N34O63
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(123B9)2-L2-PTX Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(123B9)2-L2-PTXPeptide-Drug Conjugates (PDCs)Ephrin ReceptorEphA2Peptide-drug conjugateAgonisticMDA-MB-231 cellsBreast-cancer-Metastasis mice modelMelanomasOvarian cancerBreast cancerInhibitorinhibitorinhibit

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