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Migalastat hydrochloride-<sup>15</sup>N

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7935

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Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14929A
    Migalastat hydrochloride
    1 Publications Verification

    GR181413A

    		 Glycosidase Others
    Migalastat (GR181413A free base) hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity .
    Migalastat hydrochloride
  • HY-101037S
    Sarcosine-15N

    N-Methylglycine-<sup>15sup>N; Sarcosin-<sup>15sup>N

    		 Endogenous Metabolite GlyT Cancer
    Sarcosine- 15N is the 15N-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia .
    Sarcosine-15N
  • HY-Z0283S
    Benzamide-15N

    Benzenecarboxamide-<sup>15sup>N; Phenylamide-<sup>15sup>N

    		 Endogenous Metabolite PARP Others
    Benzamide- 15N is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP) .
    Benzamide-15N
  • HY-N0623S7
    L-Tryptophan-15N

    Tryptophan-<sup>15sup>N; Tryptophane-<sup>15sup>N

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    L-Tryptophan- 15N is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
    L-Tryptophan-15N
  • HY-W740650
    Migalastat hydrochloride-15N

    GR181413A-<sup>15sup>N

    		 Isotope-Labeled Compounds Glycosidase Others
    Migalastat hydrochloride- 15N (GR181413A- 15N) is the 15N-labeled Migalastat hydrochloride (HY-14929A). Migalastat (GR181413A free base) hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity .
    Migalastat hydrochloride-15N
  • HY-14929
    Migalastat

    GR181413A free base; 1-Deoxygalactonojirimycin

    		 Glycosidase Others
    Migalastat (GR181413A free base) is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity .
    Migalastat
  • HY-B0215S1
    Acetylcysteine-15N

    N-Acetylcysteine-<sup>15sup>N; N-Acetyl-L-cysteine-<sup>15sup>N; NAC-<sup>15sup>N

    		 Isotope-Labeled Compounds Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis Ferroptosis Influenza Virus Disulfidptosis Infection Neurological Disease
    Acetylcysteine- 15N (N-Acetylcysteine- 15N) is the 15N-labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies .
    Acetylcysteine-15N
  • HY-Y0504S2
    Trimethylammonium chloride-15N

    Hegzadesil-<sup>15sup>N; Trimethylamine hydrochloric acid-<sup>15sup>N; Trimethylamine monohydrochloride-<sup>15sup>N

    		 Endogenous Metabolite Metabolic Disease
    Trimethylammonium chloride- 15N is the 15N labeled Trimethylammonium chloride . Trimethylammonium chloride is an endogenous metabolite.
    Trimethylammonium chloride-15N
  • HY-128850S5
    N-Acetyl-D-mannosamine-15N

    N-Acetylmannosamine-<sup>15sup>N; ManNAc-<sup>15sup>N

    		 Isotope-Labeled Compounds Bacterial Neurological Disease
    N-Acetyl-D-mannosamine- 15N is the 15N labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)
    N-Acetyl-D-mannosamine-15N
  • HY-N0733S4
    Glucosamine-15N hydrochloride

    D-(+)-Glucosamine-<sup>15sup>N hydrochloride; Chitosamine-<sup>15sup>N hydrochloride

    		 Isotope-Labeled Compounds Autophagy Endogenous Metabolite HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Inflammation/Immunology Cancer
    Glucosamine- 15N (hydrochloride) is the 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a
    Glucosamine-15N hydrochloride
  • HY-13599S2
    Cladribine-15N

    2-Chloro-2′-deoxyadenosine-<sup>15sup>N; Cldado-<sup>15sup>N; 2Cda-<sup>15sup>N

    		 Isotope-Labeled Compounds Apoptosis Adenosine Deaminase Cardiovascular Disease Cancer
    Cladribine- 15N (2-Chloro-2′-deoxyadenosine- 15N) is 15N labeled Cladribine. Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis .
    Cladribine-15N
  • HY-N0650S10
    L-Serine-15N

    (-)-Serine-<sup>15sup>N; (S)-Serine-<sup>15sup>N

    		 Endogenous Metabolite Cancer
    L-Serine- 15N is the 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
    L-Serine-15N
  • HY-W779021
    Adenosine-15N

    Adenine riboside-<sup>15sup>N; D-Adenosine-<sup>15sup>N

    		 Isotope-Labeled Compounds Endogenous Metabolite Nucleoside Antimetabolite/Analog Autophagy Apoptosis Metabolic Disease Cancer
    Adenosine- 15N (Adenine riboside- 15N) is 15N labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .
    Adenosine-15N
  • HY-W698472
    Hydroxyurea-15N

    Hydroxycarbamide-<sup>15sup>N

    		 Isotope-Labeled Compounds Apoptosis DNA/RNA Synthesis Autophagy HIV Orthopoxvirus Cancer
    Hydroxyurea- 15N (Hydroxycarbamide- 15N) is the 15N labeled Hydroxyurea (HY-B0313). Hydroxyurea is a cell apoptosis inducer that inhibit DNA synthesis through inhibition of ribonucleotide reductase. Hydroxyurea shows anti-orthopoxvirus activity.
    Hydroxyurea-15N
  • HY-N0305S
    5-Aminolevulinic acid-15N hydrochloride

    5-ALA-<sup>15sup>N hydrochloride; δ-Aminolevulinic acid-<sup>15sup>N hydrochloride; 5-Amino-4-oxopentanoic acid-<sup>15sup>N hydrochloride

    		 Isotope-Labeled Compounds Autophagy Mitophagy Endogenous Metabolite Apoptosis Metabolic Disease Cancer
    5-Aminolevulinic acid- 15N (hydrochloride) is the 15N-labeled 5-Aminolevulinic acid (hydrochloride). 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.
    5-Aminolevulinic acid-15N hydrochloride
  • HY-N0230S1
    β-Alanine-15N

    2-Carboxyethylamine-<sup>15sup>N; 3-Aminopropanoic acid-<sup>15sup>N

    		 Endogenous Metabolite Metabolic Disease
    β-Alanine- 15N is the 15N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
    β-Alanine-15N
  • HY-W750600
    Acetonitrile-15N

    Methyl cyanide-<sup>15sup>N

    		 Endogenous Metabolite
    Acetonitrile-15N (Methyl cyanide-15N) is a stable isotope labeled organic compound with important applications in metabolic research and molecular labeling. Acetonitrile-15N is used in biolabeling experiments to track metabolic pathways and help understand the chemical reaction mechanisms in organisms. Acetonitrile-15N is also widely used in environmental science to study the migration and transformation processes of pollutants.
    Acetonitrile-15N
  • HY-B0139AS
    Flucytosine-15N3 hydrochloride

    5-Fluorocytosine-<sup>15sup>N3 hydrochloride; NSC 103805-<sup>15sup>N3 hydrochloride; Ro 2-9915-<sup>15sup>N3 hydrochloride

    		 Isotope-Labeled Compounds Others
    Flucytosine- 15N3 hydrochloride is 15N labeled Flucytosine.
    Flucytosine-15N3 hydrochloride
  • HY-126050S
    (R)-Pantetheine-15N

    Pantetheine-<sup>15sup>N

    		 Isotope-Labeled Compounds Others
    (R)-Pantetheine- 15N (Pantetheine- 15N) is the 15N labeled (R)-Pantetheine (HY-126050). (R)-Pantetheine is the biosynthetic precursor to CoA .
    (R)-Pantetheine-15N
  • HY-W096993S1
    TPABr-N15

    Tetrapropylammonium bromide-<sup>15sup>N

    		 Isotope-Labeled Compounds Others
    TPABr (Tetrapropylammonium bromide)- 15N is the 15N labeled TPABr (Tetrapropylammonium bromide) .
    TPABr-N15
  • HY-W712567
    Adenine-15N5 hydrochloride

    6-Aminopurine-<sup>15sup>N5 hydrochloride; Vitamin B4-<sup>15sup>N5 hydrochloride

    		 Isotope-Labeled Compounds Others
    Adenine-15N5 hydrochloride (6-Aminopurine-15N5 hydrochloride) is the 15N labeled isotope of Adenine-15N5 hydrochloride (6-Aminopurine-15N5 hydrochloride; Vitamin B4-15N5 hydrochloride) .
    Adenine-15N5 hydrochloride
  • HY-D0187S6
    L-Glutathione reduced-15N

    GSH-<sup>15sup>N; γ-L-Glutamyl-L-cysteinyl-glycine-<sup>15sup>N

    		 Isotope-Labeled Compounds Others
    L-Glutathione reduced- 15N (GSH- 15N; γ-L-Glutamyl-L-cysteinyl-glycine- 15N) is 15N-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant that scavenges oxygen free radicals.
    L-Glutathione reduced-15N
  • HY-N0733S2
    Glucosamine-13C,15N hydrochloride

    D-(+)-Glucosamine-<sup>13sup>C,<sup>15sup>N hydrochloride; Chitosamine-<sup>13sup>C,<sup>15sup>N hydrochloride

    		 Isotope-Labeled Compounds Autophagy Endogenous Metabolite HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Inflammation/Immunology Cancer
    Glucosamine- 13C, 15N (hydrochloride) is the 13C and 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, i
    Glucosamine-13C,15N hydrochloride
  • HY-D0184S2
    2'-Deoxycytidine-15N3

    Deoxycytidine-<sup>15sup>N3; Cytosine deoxyriboside-<sup>15sup>N3; Deoxyribose cytidine-<sup>15sup>N3

    		 Endogenous Metabolite Others
    2'-Deoxycytidine- 15N3 is the 15N labeled 2'-Deoxycytidine . 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu) .
    2'-Deoxycytidine-15N3
  • HY-17563S4
    2'-Deoxyguanosine-15N5

    Deoxyguanosine-<sup>15sup>N5; Guanine deoxyriboside-<sup>15sup>N5

    		 Isotope-Labeled Compounds Endogenous Metabolite Cancer
    2'-Deoxyguanosine- 15N5 (Deoxyguanosine- 15N5; Guanine deoxyriboside- 15N5) is 15N labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
    2'-Deoxyguanosine-15N5
  • HY-W725311
    AMPA-15N

    (Aminomethyl)phosphonic acid-<sup>15sup>N

    		 Isotope-Labeled Compounds Others
    AMPA- 15N ((Aminomethyl)phosphonic acid- 15N) is the 15N labeled (Aminomethyl)phosphonic acid (HY-W035361).
    AMPA-15N
  • HY-N0097S3
    Guanosine-15N5

    DL-Guanosine-<sup>15sup>N5; Vernine-<sup>15sup>N5

    		 HSV Endogenous Metabolite Infection
    Guanosine- 15N5 is the 15N labeled Guanosine . Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .
    Guanosine-15N5
  • HY-N0623S8
    L-Tryptophan-15N2

    Tryptophan-<sup>15sup>N2; Tryptophane-<sup>15sup>N2

    		 Endogenous Metabolite Metabolic Disease
    L-Tryptophan- 15N2 is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .
    L-Tryptophan-15N2
  • HY-W653882
    Carbamazepine-d2,15N

    CBZ-d2,<sup>15sup>N; NSC 169864-d2,<sup>15sup>N

    		 Isotope-Labeled Compounds Others
    Carbamazepine-d2,15N is a deuterated labeled Carbamazepine-d2,15N .
    Carbamazepine-d2,15N
  • HY-N1150S9
    Thymidine-15N2

    DThyd-<sup>15sup>N2; NSC-<sup>15sup>N2

    		 DNA/RNA Synthesis Endogenous Metabolite Orthopoxvirus Cancer
    Thymidine- 15N2 is the 15N labeled Thymidine . Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication .
    Thymidine-15N2
  • HY-B0271S1
    Pyrazinamide-13C,15N

    Pyrazinecarboxamide-<sup>13sup>C,<sup>15sup>N; Pyrazinoic acid amide-<sup>13sup>C,<sup>15sup>N

    		 Autophagy Antibiotic Bacterial Isotope-Labeled Compounds Infection
    Pyrazinamide- 13C, 15N is 15N and 13C labeled Pyrazinamide (HY-B0271). Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.
    Pyrazinamide-13C,15N
  • HY-W728096
    Migalastat-d5

    GR181413A-d5 free base

    		 Isotope-Labeled Compounds Glycosidase Others
    Migalastat-d5 (GR181413A-d5 (free base)) is deuterium labeled Migalastat. Migalastat (GR181413A free base) is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity .
    Migalastat-d5
  • HY-108213S1
    Inosinic acid-15N4 dilithium

    5'-IMP<sup>15sup>N4 dilithium; IMP-<sup>15sup>N4 dilithium; Inosine 5'-(dihydrogen phosphate)-<sup>15sup>N4 dilithium

    		 Isotope-Labeled Compounds Others
    Inosinic acid- 15N4 dilithium (5'-IMP-15N4 (dilithium); IMP-15N4 (dilithium); Inosine 5'-(dihydrogen phosphate)-15N4 (dilithium)) is 15N-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .
    Inosinic acid-15N4 dilithium
  • HY-W653970
    5-Azacytidine-15N4

    Azacitidine-<sup>15sup>N4; 5-AzaC-<sup>15sup>N4; Ladakamycin-<sup>15sup>N4

    		 Isotope-Labeled Compounds Antibiotic DNA Methyltransferase Organoid Autophagy Nucleoside Antimetabolite/Analog Bacterial Infection
    5-Azacytidine- 15N4 is 13C and 15N labeled 5-Azacytidine. 5-Azacytidine (Azacitidine; 5-AzaC; Ladakamycin) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation. 5-Azacytidine is incorporated into DNA to covalently trap DNA methyltransferases and contributes to reverse epigenetic changes. 5-Azacytidine induces cell autophagy .
    5-Azacytidine-15N4
  • HY-N0091S7
    Hypoxanthine-15N4
    1 Publications Verification

    Purin-6-ol-<sup>15sup>N4; Sarcine-<sup>15sup>N4

    		 Endogenous Metabolite Others
    Hypoxanthine- 15N4 is the 15N labeled Hypoxanthine . Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia .
    Hypoxanthine-15N4
  • HY-Y0271S
    Urea-15N2

    Carbamide-<sup>15sup>N2; Carbonyldiamide-<sup>15sup>N2

    		 Endogenous Metabolite Cardiovascular Disease Cancer
    Urea- 15N2 is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
    Urea-15N2
  • HY-B0228S11
    Adenosine-15N5

    Adenine riboside-<sup>15sup>N5; D-Adenosine-<sup>15sup>N5

    		 Isotope-Labeled Compounds Cancer
    Adenosine- 15N5 (Adenine riboside- 15N5; D-Adenosine- 15N5) is the 15N labled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .
    Adenosine-15N5
  • HY-N0650S6
    L-Serine1-13C,15N

    (-)-Serine-<sup>13sup>C,<sup>15sup>N; (S)-Serine-<sup>13sup>C,<sup>15sup>N

    		 Isotope-Labeled Compounds Endogenous Metabolite Cancer
    L-Serine1- 13C, 15N is the 13C- and 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
    L-Serine1-13C,15N
  • HY-W779296
    Potassium thiocyanate-13C,15N

    Potassium rhodanide-<sup>13sup>C,<sup>15sup>N

    		 Isotope-Labeled Compounds Others
    Potassium thiocyanate- 13C, 15N (Potassium rhodanide- 13C, 15N) is 13C and 15N labeled Potassium thiocyanate .
    Potassium thiocyanate-13C,15N
  • HY-N0717S
    L-Valine-15N

    (S)-Valine-<sup>15sup>N

    		 Endogenous Metabolite Others
    L-Valine- 15N is the 15N-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid .
    L-Valine-15N
  • HY-W779386
    N-Acetylglycine-13C2,15N

    Aceturic acid-<sup>13sup>C2, <sup>15sup>N; Acetamidoacetic acid-<sup>13sup>C2, <sup>15sup>N

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    N-Acetylglycine- 13C2, 15N (Aceturic acid- 13C2, 15N) is the 13C- and 15N-labeled N-Acetylglycine (HY-Y0069). N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods. N-Acetylglycine is a flavor enhancer which elicits Monosodium glutamate (MSG)-like sensory experiencesN-Acetylglycine .
    N-Acetylglycine-13C2,15N
  • HY-B0152S4
    Adenine-15N5

    6-Aminopurine-<sup>15sup>N5; Vitamin B4-<sup>15sup>N5

    		 Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Cancer
    Adenine- 15N5 (6-Aminopurine- 15N5; Vitamin B4- 15N5) is 15N labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
    Adenine-15N5
  • HY-B0152S7
    Adenine-15N5 hydrochloride hydrate

    6-Aminopurine-<sup>15sup>N5 hydrochloride hydrate; Vitamin B4-<sup>15sup>N5 hydrochloride hydrate

    		 DNA/RNA Synthesis Isotope-Labeled Compounds Cancer
    Adenine-15N5 hydrochloride hydrate (6-Aminopurine-15N5 hydrochloride hydrate) is the deuterium labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
    Adenine-15N5 hydrochloride hydrate
  • HY-N0667S2
    L-Asparagine-15N2 monohydrate

    (-)-Asparagine-<sup>15sup>N2 monohydrate; Asn-<sup>15sup>N2 monohydrate; Asparamide-<sup>15sup>N2 monohydrate

    		 Isotope-Labeled Compounds Endogenous Metabolite Apoptosis DNA/RNA Synthesis Inflammation/Immunology
    L-Asparagine- 15N2 monohydrate is the 15N-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
    L-Asparagine-15N2 monohydrate
  • HY-Y1250S
    Fmoc-Gly-OH-15N

    Fmoc-glycine-<sup>15sup>N

    		 Isotope-Labeled Compounds Others
    Fmoc-Gly-OH- 15N is the 15N labeled Fmoc-Gly-OH .
    Fmoc-Gly-OH-15N
  • HY-W067028S
    Semicarbazide-13C,15N2 hydrochloride

    Aminourea-<sup>13sup>C,<sup>15sup>N2 hydrochloride; Hydrazinecarboxamide-<sup>13sup>C,<sup>15sup>N2 hydrochloride

    		 Isotope-Labeled Compounds Others
    Semicarbazide- 13C, 15N2 hydrochloride is 15N and 13C labeled Semicarbazide.
    Semicarbazide-13C,15N2 hydrochloride
  • HY-A0042S1
    Rufinamide-15N,d2

    CGP 33101-<sup>15sup>N,d2; E 2080-<sup>15sup>N,d2; RUF 331-<sup>15sup>N,d2

    		 Isotope-Labeled Compounds Sodium Channel Neurological Disease
    Rufinamide- 15N,d2 (CGP 33101- 15N,d2) is the deuterium and 15N labeled Rufinamide (HY-A0042).Rufinamide (CGP 33101) is an orally active antiepileptic compound that inhibits Na + current activation, inhibits neuronal hyperexcitability, and has anticonvulsant effects. Rufinamide is used in the study of Lennox-Gastaut syndrome .
    Rufinamide-15N,d2
  • HY-W778058
    Guanosine-13C,15N2

    DL-Guanosine-<sup>13sup>C,<sup>15sup>N2; Vernine-<sup>13sup>C,<sup>15sup>N2

    		 Isotope-Labeled Compounds Others
    Guanosine- 13C, 15N2 (DL-Guanosine- 13C, 15N2) is 13C and 15N labeled Guanosine .
    Guanosine-13C,15N2
  • HY-13578S
    Brivudine-13C, 15N2

    Bromovinyldeoxyuridine-<sup>13sup>C,<sup>15sup>N2; BVDU-<sup>13sup>C,<sup>15sup>N2

    		 Isotope-Labeled Compounds CMV Infection Cancer
    Brivudine- 13C, 15N2 (Bromovinyldeoxyuridine- 13C, 15N2) is 13C and 15N labeled Brivudine. Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.
    Brivudine-13C, 15N2
  • HY-D0184S6
    2'-Deoxycytidine-13C,15N3

    Deoxycytidine-<sup>13sup>C,<sup>15sup>N3; Cytosine deoxyriboside-<sup>13sup>C,<sup>15sup>N3; Deoxyribose cytidine-<sup>13sup>C,<sup>15sup>N3

    		 Isotope-Labeled Compounds Endogenous Metabolite Cancer
    2'-Deoxycytidine- 13C, 15N3 (Deoxycytidine- 13C, 15N3) is 13C and 15N labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer .
    2'-Deoxycytidine-13C,15N3

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