2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. N1,N12-Diacetylspermine dihydrochloride

N1,N12-Diacetylspermine dihydrochloride  (Synonyms: DiAcSpm dihydrochloride)

Cat. No.: HY-113374A Purity: ≥99.0%
COA
SDS
Handling Instructions Technical Support

N1,N12-Diacetylspermine dihydrochloride is a diacetylated derivative of Spermine. Upregulation of N1,N12-Diacetylspermine dihydrochloride has been linked to the incidence of cancer, making it to be a potential biomarker for cancer detection.

For research use only. We do not sell to patients.

N1,N12-Diacetylspermine dihydrochloride

N1,N12-Diacetylspermine dihydrochloride Chemical Structure

CAS No. : 77928-71-3

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Based on 1 publication(s) in Google Scholar

N1,N12-Diacetylspermine dihydrochloride Related Antibodies

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Description

N1,N12-Diacetylspermine dihydrochloride is a diacetylated derivative of Spermine. Upregulation of N1,N12-Diacetylspermine dihydrochloride has been linked to the incidence of cancer, making it to be a potential biomarker for cancer detection.

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

359.34

Formula

C14H32Cl2N4O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(NCCCNCCCCNCCCNC(C)=O)=O.[H]Cl.[H]Cl
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (278.29 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7829 mL 13.9144 mL 27.8288 mL
5 mM 0.5566 mL 2.7829 mL 5.5658 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

SDS (252 KB)

COA (242 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.7829 mL 13.9144 mL 27.8288 mL 69.5720 mL
5 mM 0.5566 mL 2.7829 mL 5.5658 mL 13.9144 mL
10 mM 0.2783 mL 1.3914 mL 2.7829 mL 6.9572 mL
15 mM 0.1855 mL 0.9276 mL 1.8553 mL 4.6381 mL
20 mM 0.1391 mL 0.6957 mL 1.3914 mL 3.4786 mL
25 mM 0.1113 mL 0.5566 mL 1.1132 mL 2.7829 mL
30 mM 0.0928 mL 0.4638 mL 0.9276 mL 2.3191 mL
40 mM 0.0696 mL 0.3479 mL 0.6957 mL 1.7393 mL
50 mM 0.0557 mL 0.2783 mL 0.5566 mL 1.3914 mL
60 mM 0.0464 mL 0.2319 mL 0.4638 mL 1.1595 mL
80 mM 0.0348 mL 0.1739 mL 0.3479 mL 0.8696 mL
100 mM 0.0278 mL 0.1391 mL 0.2783 mL 0.6957 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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N1,N12-Diacetylspermine dihydrochloride Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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N1,N12-Diacetylspermine77928-71-3DiAcSpmEndogenous MetaboliteInhibitorinhibitorinhibit

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