2. Others Neuronal Signaling Membrane Transporter/Ion Channel Immunology/Inflammation NF-κB Metabolic Enzyme/Protease Apoptosis Anti-infection
  3. Reference Standards TRP Channel Amyloid-β Toll-like Receptor (TLR) Keap1-Nrf2 Heme Oxygenase (HO) Dihydroorotate Dehydrogenase Ferroptosis PAI-1 NF-κB Proton Pump Glutathione Peroxidase Thrombin Insecticide Bacterial
  4. Pellitorine (Standard)

Pellitorine (Standard) is the analytical standard of Pellitorine (HY-N3097). Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria.

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Pellitorine (Standard)

Pellitorine (Standard) Chemical Structure

CAS No. : 18836-52-7

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Pellitorine (Standard) is the analytical standard of Pellitorine (HY-N3097). Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria.

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CC(C)CNC(/C=C/C=C/CCCCC)=O
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Keywords:

Pellitorine (Standard)18836-52-7Reference StandardsTRP ChannelAmyloid-βToll-like Receptor (TLR)Keap1-Nrf2Heme Oxygenase (HO)Dihydroorotate DehydrogenaseFerroptosisPAI-1NF-κBProton PumpGlutathione PeroxidaseThrombinInsecticideBacterialTransient receptor potential channelsβ-amyloid peptideAβAbetaHeme OxygenaseDHODHPlasminogen activator inhibitor-1Nuclear factor-κBNuclear factor-kappaBPiper nigrumAlkaloidscytotoxicityMicrobial transformationAspergillus nigerInhibitorinhibitorinhibit

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