1. GPCR/G Protein Membrane Transporter/Ion Channel Neuronal Signaling
  2. Dopamine Receptor TRP Channel
  3. N-Palmitoyl dopamine

N-Palmitoyl dopamine  (Synonyms: PALDA)

Cat. No.: HY-108455 Purity: 98.88%
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N-Palmitoyl dopamine (PALDA) is a endogenous, long-chain, linear fatty acid dopamide, which is inactive on TRPV1. N-Palmitoyl dopamine displays 'entourage' effects on endovanilloids N-arachidonoyl-dopamine (NADA) and anandamide.

For research use only. We do not sell to patients.

N-Palmitoyl dopamine Chemical Structure

N-Palmitoyl dopamine Chemical Structure

CAS No. : 136181-87-8

Size Price Stock Quantity
Solvent
5 mg (2.55 mM * 5 mL in Ethanol) In-stock
Solvent
10 mg (2.55 mM * 10 mL in Ethanol) In-stock

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Description

N-Palmitoyl dopamine (PALDA) is a endogenous, long-chain, linear fatty acid dopamide, which is inactive on TRPV1. N-Palmitoyl dopamine displays 'entourage' effects on endovanilloids N-arachidonoyl-dopamine (NADA) and anandamide[1].

In Vitro

PALDA (0.1-10 μM), the EC50 of N-arachidonoyl-dopamine (NADA) is lowered from approximately 90 to approximately 30 nM. The effect on intracellular Ca2+ by another endovanilloid, N-arachidonoyl-ethanolamine (anandamide, 50 nM), is also enhanced dose-dependently by PALDA. PALDA also acted in synergy with low pH (6.0-6.7) to enhance intracellular Ca2+ via TRPV1[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

391.59

Formula

C24H41NO3

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CCCCCCCCCCCCCCCC(NCCC1=CC=C(O)C(O)=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Purity & Documentation
References
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N-Palmitoyl dopamine
Cat. No.:
HY-108455
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