IL-23R inhibitor peptide-1

Name: IL-23R inhibitor peptide-1
Brand: MedChemExpress
SKU: HY-P10723
Rating: 4.5 (1 reviews)

Cat. No.: HY-P10723 Purity: 99.85%: Data Sheet
COA

SDS
Handling Instructions
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Technical Support

IL-23R inhibitor peptide-1 (comp 475) is an interleukin-23 receptor inhibitor, with an IC₅₀ of 0.0069 μM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

IL-23R inhibitor peptide-1 Chemical Structure

CAS No. : 2894052-23-2

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IL-23R inhibitor peptide-1 (comp 475) is an interleukin-23 receptor inhibitor, with an IC₅₀ of 0.0069 μM^[1].

Molecular Weight

1897.18

Formula

C₉₁H₁₂₁N₁₉O₂₂S₂

CAS No.

2894052-23-2

Appearance

Solid

Color

White to off-white

Sequence

Ac-Pen-N-T-7MeW-Lys(Ac)-Pen-AEF-2Nal-THP-E-N-F-Sar-NH2 (Disulfide bridge:Pen1-Pen6)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 50 mg/mL (26.35 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.5271 mL	2.6355 mL	5.2710 mL
5 mM	0.1054 mL	0.5271 mL	1.0542 mL
10 mM	0.0527 mL	0.2635 mL	0.5271 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.85%

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Data Sheet (283 KB) SDS (252 KB)

COA (273 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Chengzao Sun, et al. Peptide inhibitors of interleukin-23 receptor. Patent WO2023288028.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.5271 mL	2.6355 mL	5.2710 mL	13.1775 mL
	5 mM	0.1054 mL	0.5271 mL	1.0542 mL	2.6355 mL
	10 mM	0.0527 mL	0.2635 mL	0.5271 mL	1.3177 mL
	15 mM	0.0351 mL	0.1757 mL	0.3514 mL	0.8785 mL
	20 mM	0.0264 mL	0.1318 mL	0.2635 mL	0.6589 mL
	25 mM	0.0211 mL	0.1054 mL	0.2108 mL	0.5271 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.