MRS 1523 (Standard)

Cat. No.: HY-121119R Purity: ≥98%: Handling Instructions
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MRS 1523 (Standard) is the analytical standard of MRS 1523. This product is intended for research and analytical applications. MRS 1523 is a potent and selective adenosine A3 receptor antagonist with Ki values of 18.9 nM and 113 nM for human and rat A3 receptors, respectively. In rat this corresponds to selectivities of 140- and 18-fold vs A1 and A2A receptors, respectively. MRS 1523 can exert antihyperalgesic effect through N-type Ca channel block and action potential inhibition in isolated rat dorsal root ganglion (DRG) neurons.

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MRS 1523 (Standard) Chemical Structure

CAS No. : 212329-37-8

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Description	MRS 1523 (Standard) is the analytical standard of MRS 1523 . This product is intended for research and analytical applications. MRS 1523 is a potent and selective adenosine A3 receptor antagonist with Ki values of 18.9 nM and 113 nM for human and rat A3 receptors, respectively. In rat this corresponds to selectivities of 140- and 18-fold vs A1 and A2A receptors, respectively. MRS 1523 can exert antihyperalgesic effect through N-type Ca channel block and action potential inhibition in isolated rat dorsal root ganglion (DRG) neurons.
Molecular Weight	399.55
Formula	C₂₃H₂₉NO₃S
CAS No.	212329-37-8
SMILES	O=C(OCCC)C1=C(C(C(SCC)=O)=C(N=C1C2=CC=CC=C2)CC)CCC
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

MRS 1523 (Standard) Related Classifications

Neurological Disease Inflammation/Immunology Cardiovascular Disease

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MRS 1523 (Standard)212329-37-8Adenosine ReceptorCalcium ChannelP1 receptorCa2+ channelsCa channelsA3-receptormigrationantihyperalgesicN-typeCa-channelneuronsInhibitorinhibitorinhibit

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MRS 1523 (Standard)

Product Information

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MRS 1523 (Standard) Related Classifications

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