2. PROTAC
  3. PROTAC Linkers
  4. N-Boc-7-aminoheptanoic acid

Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

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N-Boc-7-aminoheptanoic acid Chemical Structure

N-Boc-7-aminoheptanoic acid Chemical Structure

CAS No. : 60142-89-4

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N-Boc-7-aminoheptanoic acid Related Antibodies

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Description

Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Molecular Weight

245.32

Formula

C12H23NO4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCCCCCNC(OC(C)(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Purity & Documentation

Purity: ≥98.0%

COA (241 KB) HNMR (119 KB)

Handling Instructions (2659 KB)
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N-Boc-7-aminoheptanoic acid Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Boc-7-aminoheptanoic acid60142-89-4PROTAC LinkersInhibitorinhibitorinhibit

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