1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-Proline-13C5,15N

L-Proline-13C5,1-15N is the 13C- and 15N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

For research use only. We do not sell to patients.

L-Proline-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N Chemical Structure

L-Proline-13C5,15N Chemical Structure

CAS No. : 202407-23-6

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Based on 1 publication(s) in Google Scholar

Other Forms of L-Proline-13C5,15N:

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Description

L-Proline-13C5,1-15N is the 13C- and 15N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

121.09

Formula

13C5H915NO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[13C]([13C@H]1[15NH][13CH2][13CH2][13CH2]1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (825.83 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.2583 mL 41.2916 mL 82.5832 mL
5 mM 1.6517 mL 8.2583 mL 16.5166 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.60%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 8.2583 mL 41.2916 mL 82.5832 mL 206.4580 mL
5 mM 1.6517 mL 8.2583 mL 16.5166 mL 41.2916 mL
10 mM 0.8258 mL 4.1292 mL 8.2583 mL 20.6458 mL
15 mM 0.5506 mL 2.7528 mL 5.5055 mL 13.7639 mL
20 mM 0.4129 mL 2.0646 mL 4.1292 mL 10.3229 mL
25 mM 0.3303 mL 1.6517 mL 3.3033 mL 8.2583 mL
30 mM 0.2753 mL 1.3764 mL 2.7528 mL 6.8819 mL
40 mM 0.2065 mL 1.0323 mL 2.0646 mL 5.1615 mL
50 mM 0.1652 mL 0.8258 mL 1.6517 mL 4.1292 mL
60 mM 0.1376 mL 0.6882 mL 1.3764 mL 3.4410 mL
80 mM 0.1032 mL 0.5161 mL 1.0323 mL 2.5807 mL
100 mM 0.0826 mL 0.4129 mL 0.8258 mL 2.0646 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
L-Proline-13C5,15N
Cat. No.:
HY-Y0252S4
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