2. Others PI3K/Akt/mTOR Apoptosis Epigenetics Immunology/Inflammation NF-κB Cell Cycle/DNA Damage Autophagy
  3. PARP Pyroptosis Autophagy Keap1-Nrf2 NF-κB Reference Standards NOD-like Receptor (NLR) Sirtuin Apoptosis AMPK
  4. Sweroside (Standard)

Sweroside (Standard) is the analytical standard of Sweroside (HY-N0806). This product is intended for research and analytical applications. Sweroside is an iridoid glycoside that targets multiple targets, including the Keap1/Nrf2 axis, NLRP3 inflammasome, SIRT1, NF-κB, AMPK/mTOR pathway, and caspase family. Sweroside promotes Nrf2 nuclear translocation by competitively binding to Keap1. Sweroside also inhibits oxidative stress and NLRP3-mediated pyroptosis by activating Nrf2, inhibits NF-κB inflammatory pathway by activating SIRT1, and promotes autophagy and induces caspase-dependent apoptosis via the AMPK/mTOR pathway. Sweroside has antioxidant, anti-inflammatory, anti-apoptotic, and lipid metabolism regulating activities, and can be used in the research of myocardial ischemia-reperfusion injury, leukemia, acute lung injury, non-alcoholic fatty liver disease, and other fields.

For research use only. We do not sell to patients.

Sweroside (Standard) Chemical Structure

Sweroside (Standard) Chemical Structure

CAS No. : 14215-86-2

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Description

Sweroside (Standard) is the analytical standard of Sweroside (HY-N0806). This product is intended for research and analytical applications. Sweroside is an iridoid glycoside that targets multiple targets, including the Keap1/Nrf2 axis, NLRP3 inflammasome, SIRT1, NF-κB, AMPK/mTOR pathway, and caspase family. Sweroside promotes Nrf2 nuclear translocation by competitively binding to Keap1. Sweroside also inhibits oxidative stress and NLRP3-mediated pyroptosis by activating Nrf2, inhibits NF-κB inflammatory pathway by activating SIRT1, and promotes autophagy and induces caspase-dependent apoptosis via the AMPK/mTOR pathway. Sweroside has antioxidant, anti-inflammatory, anti-apoptotic, and lipid metabolism regulating activities, and can be used in the research of myocardial ischemia-reperfusion injury, leukemia, acute lung injury, non-alcoholic fatty liver disease, and other fields.

Molecular Weight

358.34

Formula

C₁₆H₂₂O₉
CAS No.
SMILES

C=C[C@@H]1[C@@](CCOC2=O)([H])C2=CO[C@H]1O[C@]([C@@H]([C@@H](O)[C@@H]3O)O)([H])O[C@@H]3CO
Structure Classification
Initial Source
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Sweroside (Standard) Related Classifications

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Keywords:

Sweroside (Standard)14215-86-2PARPPyroptosisAutophagyKeap1-Nrf2NF-κBReference StandardsNOD-like Receptor (NLR)SirtuinApoptosisAMPKpoly ADP ribose polymerase Nuclear factor-κBNuclear factor-kappaBAMP-activated protein kinaseInhibitorinhibitorinhibit

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