N-Boc-2-pyrroleboronic acid

Cat. No.: HY-32959 Purity: 99.65%: Data Sheet
COA

SDS
Handling Instructions
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N-Boc-2-pyrroleboronic acid is an organic synthesis intermediate used primarily in the synthesis of chiral pharmaceutical molecules and biologically active molecules. The boronic acid on the pyrrole ring can participate in Suzuki coupling reactions. The boronic acid can be oxidized to a hydroxyl group under the action of nitrogen oxides, and after tautomerization, it can be further transformed into 2-oxo-2,5-dihydro-1-pyrrolecarboxylic acid tert-butyl ester.

For research use only. We do not sell to patients.

N-Boc-2-pyrroleboronic acid Chemical Structure

CAS No. : 135884-31-0

Size	Stock	Quantity
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

211.03

Formula

C₉H₁₄BNO₄

CAS No.

135884-31-0

Appearance

Solid

Color

White to off-white

SMILES

O=C(N1C(B(O)O)=CC=C1)OC(C)(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 175 mg/mL (829.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.7388 mL	23.6938 mL	47.3875 mL
5 mM	0.9478 mL	4.7388 mL	9.4775 mL
10 mM	0.4739 mL	2.3694 mL	4.7388 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.97%

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Data Sheet (276 KB) SDS (393 KB)

COA (256 KB) HNMR (118 KB) RP-HPLC (197 KB)

Handling Instructions (2659 KB)

References

[1]. Tsutomu Fukuda, et al. synthesis and evaluation of topoisomerase I inhibitors possessing the 5,13-dihydro-6H-benzo[6,7]indolo[3,2-c]-quinolin-6-one scaffold. Heterocycles, 99(2, Spec. Issue), 1032-1052; 2019.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.7388 mL	23.6938 mL	47.3875 mL	118.4688 mL
	5 mM	0.9478 mL	4.7388 mL	9.4775 mL	23.6938 mL
	10 mM	0.4739 mL	2.3694 mL	4.7388 mL	11.8469 mL
	15 mM	0.3159 mL	1.5796 mL	3.1592 mL	7.8979 mL
	20 mM	0.2369 mL	1.1847 mL	2.3694 mL	5.9234 mL
	25 mM	0.1896 mL	0.9478 mL	1.8955 mL	4.7388 mL
	30 mM	0.1580 mL	0.7898 mL	1.5796 mL	3.9490 mL
	40 mM	0.1185 mL	0.5923 mL	1.1847 mL	2.9617 mL
	50 mM	0.0948 mL	0.4739 mL	0.9478 mL	2.3694 mL
	60 mM	0.0790 mL	0.3949 mL	0.7898 mL	1.9745 mL
	80 mM	0.0592 mL	0.2962 mL	0.5923 mL	1.4809 mL
	100 mM	0.0474 mL	0.2369 mL	0.4739 mL	1.1847 mL