2. Others Anti-infection MAPK/ERK Pathway NF-κB Immunology/Inflammation Metabolic Enzyme/Protease
  3. Reference Standards Bacterial p38 MAPK NF-κB NO Synthase Reactive Oxygen Species (ROS)
  4. Swertianolin (Standard)

Swertianolin (Standard) is the analytical standard of Swertianolin (HY-N2192). This product is intended for research and analytical applications. Swertianolin is a xanthone glycoside. Swertianolin can be isolated from plants of the Gentianaceae family (e.g., Gentiana campestris and Swertia punicea). Swertianolin inhibits p38 phosphorylation and NF-κB activation, and reduces NO and ROS production. Swertianolin exhibits anti-Helicobacter pylori activity with an IC50 of 6.1 μM and a minimum bactericidal concentration of 91.7 μM. Swertianolin modulates immune function in sepsis. Swertianolin is useful in the research of diseases such as Alzheimer's disease, hepatitis B, Helicobacter pylori infection, and sepsis.

For research use only. We do not sell to patients.

Swertianolin (Standard)

Swertianolin (Standard) Chemical Structure

CAS No. : 23445-00-3

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Information

Swertianolin (Standard) is the analytical standard of Swertianolin (HY-N2192). This product is intended for research and analytical applications. Swertianolin is a xanthone glycoside. Swertianolin can be isolated from plants of the Gentianaceae family (e.g., Gentiana campestris and Swertia punicea). Swertianolin inhibits p38 phosphorylation and NF-κB activation, and reduces NO and ROS production. Swertianolin exhibits anti-Helicobacter pylori activity with an IC50 of 6.1 μM and a minimum bactericidal concentration of 91.7 μM. Swertianolin modulates immune function in sepsis. Swertianolin is useful in the research of diseases such as Alzheimer's disease, hepatitis B, Helicobacter pylori infection, and sepsis.

Molecular Weight

436.37

Formula

C20H20O11
CAS No.
SMILES

O=C1C2=C(OC3=C1C(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=CC=C3O)C=C(OC)C=C2O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Swertianolin (Standard) Related Classifications

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Keywords:

Swertianolin (Standard)23445-00-3Reference StandardsBacterialp38 MAPKNF-κBNO SynthaseReactive Oxygen Species (ROS)Nuclear factor-κBNuclear factor-kappaBNitric oxide synthasesNOSInhibitorinhibitorinhibit

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