KDM6A Antibody (YA3532)

Cat. No.: HY-P83835: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
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KDM6A Antibody (YA3532) is a mouse-derived and non-conjugated IgG2a antibody, targeting to KDM6A. It can be applicated for WB, ELISA assays, in the background of human, rat.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
Properties
Documentation

Description	KDM6A Antibody (YA3532) is a mouse-derived and non-conjugated IgG2a antibody, targeting to KDM6A. It can be applicated for WB, ELISA assays, in the background of human, rat.
Background	KDM6A is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, playing a central role in the histone code. It demethylates trimethylated and dimethylated, but not monomethylated, H3 'Lys-27'. KDM6A is crucial in regulating posterior development by controlling HOX gene expression. The demethylation of H3 'Lys-27' coincides with methylation of H3 'Lys-4' and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A. Additionally, KDM6A functions independently of its demethylase activity in chromatin remodeling to regulate T-box family member-dependent gene expression (by similar).
Gene ID	7403 [NCBI]
SwissProt ID	O15550
Synonyms	UTX; KABUK2; bA386N14.2
Molecular Weight	Predicted band size: 154 kDa; Observed band size: 154 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human, Rat
Dilution Ratio	WB: 1/500-1/2000; ELISA: 1/10000
Application	WB, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG2a
Immunogen	Purified recombinant fragment of human KDM6A (AA: 1252-1401) expressed in E. Coli.
Documentation	Select Batch: Data Sheet (234 KB) SDS (251 KB) COA (191 KB) User Guide for Antibodies (1077 KB)

KDM6A Antibody (YA3532) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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KDM6A Antibody (YA3532)

Biological Activity

Technical Parameters

Properties

Documentation

KDM6A Antibody (YA3532) Related Classifications

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