2. Others Metabolic Enzyme/Protease Apoptosis Cell Cycle/DNA Damage
  3. Reference Standards Endogenous Metabolite Apoptosis DNA/RNA Synthesis
  4. L-Asparagine (Standard)

L-Asparagine (Standard)  (Synonyms: (-)-Asparagine (Standard); Asn (Standard); Asparamide (Standard))

Cat. No.: HY-N0667R Purity: 99.91%
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L-Asparagine (Standard) is the analytical standard of L-Asparagine (HY-N0667). This product is intended for research and analytical applications. L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.

For research use only. We do not sell to patients.

L-Asparagine (Standard)

L-Asparagine (Standard) Chemical Structure

CAS No. : 70-47-3

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Information

L-Asparagine (Standard) is the analytical standard of L-Asparagine (HY-N0667). This product is intended for research and analytical applications. L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

132.12

Formula

C4H8N2O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N[C@H](C(O)=O)CC(N)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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L-Asparagine (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Asparagine (Standard)70-47-3(-)-Asparagine (Standard)Asn (Standard)Asparamide (Standard)Reference StandardsEndogenous MetaboliteApoptosisDNA/RNA SynthesisAsparagine IPEC-J2AntitumorODCInhibitorinhibitorinhibit

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