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  3. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine  (Synonyms: THEED; THEEN)

Cat. No.: HY-W047709 Purity: 99.89%
Handling Instructions Technical Support

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine (THEED) is a tetrapod ligand-type copper ionophore with anticancer activity. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine inhibits MCF-7 cells with IC50=23 μg/mL.

For research use only. We do not sell to patients.

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine Chemical Structure

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine Chemical Structure

CAS No. : 140-07-8

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Description

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine (THEED) is a tetrapod ligand-type copper ionophore with anticancer activity. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine inhibits MCF-7 cells with IC50=23 μg/mL[1].

Molecular Weight

236.31

Formula

C10H24N2O4

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

OCCN(CCO)CCN(CCO)CCO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (846.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2317 mL 21.1586 mL 42.3173 mL
5 mM 0.8463 mL 4.2317 mL 8.4635 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.2317 mL 21.1586 mL 42.3173 mL 105.7932 mL
5 mM 0.8463 mL 4.2317 mL 8.4635 mL 21.1586 mL
10 mM 0.4232 mL 2.1159 mL 4.2317 mL 10.5793 mL
15 mM 0.2821 mL 1.4106 mL 2.8212 mL 7.0529 mL
20 mM 0.2116 mL 1.0579 mL 2.1159 mL 5.2897 mL
25 mM 0.1693 mL 0.8463 mL 1.6927 mL 4.2317 mL
30 mM 0.1411 mL 0.7053 mL 1.4106 mL 3.5264 mL
40 mM 0.1058 mL 0.5290 mL 1.0579 mL 2.6448 mL
50 mM 0.0846 mL 0.4232 mL 0.8463 mL 2.1159 mL
60 mM 0.0705 mL 0.3526 mL 0.7053 mL 1.7632 mL
80 mM 0.0529 mL 0.2645 mL 0.5290 mL 1.3224 mL
100 mM 0.0423 mL 0.2116 mL 0.4232 mL 1.0579 mL
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N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine
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