Chromogranin A Antibody (YA5678)

Chromogranin A Antibody (YA5678) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Chromogranin A. It can be applicated for IHC-P, ELISA assays, in the background of human, mouse.

CHGA protein exerts a strong inhibitory effect on glucose-induced insulin release from the pancreas. It functions as a non-competitive nicotinic cholinergic antagonist, inhibiting catecholamine release from chromaffin cells and noradrenergic neurons. Additionally, CHGA displays antibacterial activity against both Gram-positive (S. aureus and M. luteus) and Gram-negative bacteria (E. coli and P. aeruginosa). Moreover, it has the capacity to induce mast cell migration, degranulation, and the production of cytokines and chemokines. Furthermore, CHGA acts as a potent scavenger of free radicals in vitro and may play a role in the regulation of cardiac function and blood pressure.

P10645

Predicted band size: 51 kDa; Observed band size: 70 kDa

affinity chromatography.

Non-conjugated

Unmodified

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse,

IHC: 1:200-400; ELISA: 1:500-5000

IHC-P, ELISA

Liquid

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Synthesized peptide derived from human Chromogranin A AA range: 19-94