2. Metabolic Enzyme/Protease
  3. Liposome
  4. N-Sterol

N-Sterol is a sterol lipid that has been used to generate lipid nanoparticles (LNPs) for delivery of mRNA in vitro and in vivo. N-Sterol LNPs are taken up in J774A.1 macrophages in a lipid composition-dependent manner via clathrin caveolae, caveolin-mediated endocytosis, micropinocytosis, or phagocytosis at different frequencies.

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N-Sterol Chemical Structure

N-Sterol Chemical Structure

CAS No. : 3069417-18-8

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N-Sterol Related Antibodies

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Description

N-Sterol is a sterol lipid that has been used to generate lipid nanoparticles (LNPs) for delivery of mRNA in vitro and in vivo. N-Sterol LNPs are taken up in J774A.1 macrophages in a lipid composition-dependent manner via clathrin caveolae, caveolin-mediated endocytosis, micropinocytosis, or phagocytosis at different frequencies[1].

Molecular Weight

527.82

Formula

C34H57NO3
CAS No.
SMILES

O=C(/C=C/N(CCOC)C)O[C@H]1CC[C@@]2([C@]3(CC[C@@]4([C@]([H])(CC[C@]4([C@@]3(CC=C2C1)[H])[H])[C@@H](CCCC(C)C)C)C)[H])C
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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N-Sterol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Sterol3069417-18-8LiposomeJ774A.1LNPmRNAInhibitorinhibitorinhibit

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