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  3. Ethyl cellulose

Ethyl cellulose  (Synonyms: Ethyl cellulose N-200)

Cat. No.: HY-W115746
Handling Instructions Technical Support

Ethyl cellulose is a derivative of cellulose. Ethyl cellulose is a non-toxic, biodegradable polymer. Ethyl cellulose has unique properties such as oil gel formation, active ingredient delivery and film formation. Ethyl cellulose can be used as a pharmaceutical excipient, such as a coating agent, flavoring agent, tablet filler, etc. Ethyl cellulose can be used to prepare nanoparticles for active compound delivery.

For research use only. We do not sell to patients.

Ethyl cellulose Chemical Structure

Ethyl cellulose Chemical Structure

CAS No. : 9004-57-3

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Ethyl cellulose is a derivative of cellulose. Ethyl cellulose is a non-toxic, biodegradable polymer. Ethyl cellulose has unique properties such as oil gel formation, active ingredient delivery and film formation. Ethyl cellulose can be used as a pharmaceutical excipient, such as a coating agent, flavoring agent, tablet filler, etc. Ethyl cellulose can be used to prepare nanoparticles for active compound delivery[1][2][3][4].

In Vitro

Ethyl cellulose-stabilized silver nanoparticles (AgNPs-EC) have an inhibitory effect on TNF-α mRNA and protein expression levels in MCF-7 cells[3].
Ethyl cellulose is used to prepare nanoparticles showing anti-H. pylori activity[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Ethyl cellulose nanoparticles loaded with Clarithromycin (30 mg/kg body weight; p.o.; once a day; 3 days) significantly enhance the H. pylori clearance in the stomach of C57BL/6 mice infected with H. pylori compared to free Clarithromycin (HY-17508)[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Ethyl Cellulose]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 16.67 mg/mL (ultrasonic and warming and heat to 60°C)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% EtOH    90% Corn Oil

    Solubility: ≥ 1.67 mg/mL; Clear solution

    This protocol yields a clear solution of ≥ 1.67 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

    Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (16.7 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ethyl cellulose
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HY-W115746
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