1. Cell Cycle/DNA Damage Epigenetics Stem Cell/Wnt
  2. HDAC YAP
  3. HDAC11-IN-1 TFA

HDAC11-IN-1 (Compound 14-NC6OH) TFA is a selective macrocyclic inhibitor of HDAC11 with a Ki of 40 nM. HDAC11-IN-1 TFA exhibits good cell permeability and can inhibit the expression of YAP1 and SOX2.

For research use only. We do not sell to patients.

HDAC11-IN-1 TFA Chemical Structure

HDAC11-IN-1 TFA Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Description

HDAC11-IN-1 (Compound 14-NC6OH) TFA is a selective macrocyclic inhibitor of HDAC11 with a Ki of 40 nM. HDAC11-IN-1 TFA exhibits good cell permeability and can inhibit the expression of YAP1 and SOX2[1].

Molecular Weight

995.15

Formula

C45H64F6N6O8S2

SMILES

FC(F)(C1=CC=CC=C1C[C@@H](C(N[C@@H]([C@H](CC)C)C(N[C@@H](CCCCCC(N(CCCCCC)O)=O)C(NCCCSC2)=O)=O)=O)NC(CCSCC3=CC=CC2=N3)=O)F.O=C(O)C(F)(F)F

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
HDAC11-IN-1 TFA
Cat. No.:
HY-173076A
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