5-(N,N-Hexamethylene)-amiloride (Standard)

Cat. No.: HY-128067R Purity: ≥98%: Handling Instructions
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5-(N,N-Hexamethylene)-amiloride (Standard) is the analytical standard of 5-(N,N-Hexamethylene)-amiloride. This product is intended for research and analytical applications. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively.

For research use only. We do not sell to patients.

5-(N,N-Hexamethylene)-amiloride (Standard) Chemical Structure

CAS No. : 1428-95-1

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Description	5-(N,N-Hexamethylene)-amiloride (Standard) is the analytical standard of 5-(N,N-Hexamethylene)-amiloride . This product is intended for research and analytical applications. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively.
Molecular Weight	311.77
Formula	C₁₂H₁₈ClN₇O
CAS No.	1428-95-1
SMILES	O=C(C1=NC(Cl)=C(N2CCCCCC2)N=C1N)NC(N)=N
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

5-(N,N-Hexamethylene)-amiloride (Standard) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-(N,N-Hexamethylene)-amiloride (Standard)1428-95-1Sodium ChannelHIVApoptosisNa channelsNa+ channelsHuman immunodeficiency virusleukemic cellsHCoV229EMHVmouse hepatitis virusVpu virus ion channelInhibitorinhibitorinhibit

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5-(N,N-Hexamethylene)-amiloride (Standard)

Product Information

Purity & Documentation

Customer Review

5-(N,N-Hexamethylene)-amiloride (Standard) Related Classifications

Molarity Calculator

Dilution Calculator