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  3. Methacrylic acid N-hydroxysuccinimide ester

Methacrylic acid N-hydroxysuccinimide ester  (Synonyms: NHS-MA)

Cat. No.: HY-W105423 Purity: 99.99%
Handling Instructions Technical Support

Methacrylic acid N-hydroxysuccinimide ester (NHS-MA) ios used as a monomer to prepare degradable amphiphilic block copolymer microparticles via RAFT polymerization for low pH-triggered drug delivery.

For research use only. We do not sell to patients.

Methacrylic acid N-hydroxysuccinimide ester

Methacrylic acid N-hydroxysuccinimide ester Chemical Structure

CAS No. : 38862-25-8

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Based on 1 publication(s) in Google Scholar

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Description

Methacrylic acid N-hydroxysuccinimide ester (NHS-MA) ios used as a monomer to prepare degradable amphiphilic block copolymer microparticles via RAFT polymerization for low pH-triggered drug delivery[1].

Molecular Weight

183.16

Formula

C8H9NO4

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

C=C(C)C(=O)ON1C(=O)CCC1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (545.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4597 mL 27.2985 mL 54.5971 mL
5 mM 1.0919 mL 5.4597 mL 10.9194 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.99%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.4597 mL 27.2985 mL 54.5971 mL 136.4927 mL
5 mM 1.0919 mL 5.4597 mL 10.9194 mL 27.2985 mL
10 mM 0.5460 mL 2.7299 mL 5.4597 mL 13.6493 mL
15 mM 0.3640 mL 1.8199 mL 3.6398 mL 9.0995 mL
20 mM 0.2730 mL 1.3649 mL 2.7299 mL 6.8246 mL
25 mM 0.2184 mL 1.0919 mL 2.1839 mL 5.4597 mL
30 mM 0.1820 mL 0.9100 mL 1.8199 mL 4.5498 mL
40 mM 0.1365 mL 0.6825 mL 1.3649 mL 3.4123 mL
50 mM 0.1092 mL 0.5460 mL 1.0919 mL 2.7299 mL
60 mM 0.0910 mL 0.4550 mL 0.9100 mL 2.2749 mL
80 mM 0.0682 mL 0.3412 mL 0.6825 mL 1.7062 mL
100 mM 0.0546 mL 0.2730 mL 0.5460 mL 1.3649 mL
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Methacrylic acid N-hydroxysuccinimide ester Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Methacrylic acid N-hydroxysuccinimide ester
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