(R)-Amino-N-benzyl-3-methoxypropionamide

Cat. No.: HY-I0169 Purity: 99.85% ee.: 98.77%: Data Sheet
SDS

COA
Handling Instructions
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(R)-Amino-N-benzyl-3-methoxypropionamide is a stable intermediate of Lacosamide (an antiepileptic drug).

For research use only. We do not sell to patients.

(R)-Amino-N-benzyl-3-methoxypropionamide Chemical Structure

CAS No. : 196601-69-1

Size	Stock	Quantity
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
250 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	Get quote
10 g	Get quote

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Description

(R)-Amino-N-benzyl-3-methoxypropionamide is a stable intermediate of Lacosamide (an antiepileptic drug)^[1].

Molecular Weight

208.26

Formula

C₁₁H₁₆N₂O₂

CAS No.

196601-69-1

Appearance

Solid-Liquid Mixture

Color

Colorless to off-white

SMILES

O=C(NCC1=CC=CC=C1)[C@H](N)COC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (480.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8017 mL	24.0085 mL	48.0169 mL
5 mM	0.9603 mL	4.8017 mL	9.6034 mL
10 mM	0.4802 mL	2.4008 mL	4.8017 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.85% ee.: 98.77%

Select Batch:

Data Sheet (267 KB) SDS (393 KB)

COA (246 KB) HNMR (114 KB) RP-HPLC (225 KB) NP-HPLC (170 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. Anjiang Yang, et al. Improved Synthesis and Impurity Identification of (R)-Lacosamide. Organic Process Research & Development. 2019, 23, 5, 818–824.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.8017 mL	24.0085 mL	48.0169 mL	120.0423 mL
	5 mM	0.9603 mL	4.8017 mL	9.6034 mL	24.0085 mL
	10 mM	0.4802 mL	2.4008 mL	4.8017 mL	12.0042 mL
	15 mM	0.3201 mL	1.6006 mL	3.2011 mL	8.0028 mL
	20 mM	0.2401 mL	1.2004 mL	2.4008 mL	6.0021 mL
	25 mM	0.1921 mL	0.9603 mL	1.9207 mL	4.8017 mL
	30 mM	0.1601 mL	0.8003 mL	1.6006 mL	4.0014 mL
	40 mM	0.1200 mL	0.6002 mL	1.2004 mL	3.0011 mL
	50 mM	0.0960 mL	0.4802 mL	0.9603 mL	2.4008 mL
	60 mM	0.0800 mL	0.4001 mL	0.8003 mL	2.0007 mL
	80 mM	0.0600 mL	0.3001 mL	0.6002 mL	1.5005 mL
	100 mM	0.0480 mL	0.2401 mL	0.4802 mL	1.2004 mL