C16 Ganglioside GM1 (d18:1/16:0)  (Synonyms: C16-GM1; N-Hexadecaoyl (13,13,14,14,15,15,16,16,16)-moosialogaglioside GM1)

C16 Ganglioside GM1 (d18:1/16:0) (C16-GM1) is a member of the ganglioside family containing saturated C16:0 acyl chains. C16 Ganglioside GM1 (d18:1/16:0) serves as a functional receptor for Cholera toxin (HY-P1446) B subunit, while showing reduced efficiency in both transcytosis and retrograde pathways. C16 Ganglioside GM1 (d18:1/16:0) can be used for diarrheal diseases research^[1].

1518.77

C₇₁H₁₂₇N₃O₃₁

165615-97-4

OC[C@@H](O[C@H]1OC[C@H](NC(CCCCCCCCCCCCCCC)=O)[C@@H](/C=C/CCCCCCCCCCCCC)O)[C@@H](O[C@H]2[C@H](O)[C@@H](O[C@@]3(C[C@@H]([C@H]([C@@]([H])(O3)[C@H](O)[C@@H](CO)O)NC(C)=O)O)C(O)=O)[C@@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O[C@H]5[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O5)[C@H]4NC(C)=O)[C@@H](CO)O2)[C@H](O)[C@H]1O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Saslowsky DE, et al. Ganglioside GM1-mediated transcytosis of cholera toxin bypasses the retrograde pathway and depends on the structure of the ceramide domain. J Biol Chem. 2013 Sep 6;288(36):25804-25809.  [Content Brief]