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Mer-NF5003E is a non-nucleoside reverse transcriptase inhibitor targeting HIV-1 reverse transcriptase (RT) (EC50=50 μM). Mer-NF5003E exhibits inhibitory activity against wild-type HIV-1 and multiple NNRTI-resistant strains (e.g., K103N, Y181C). Mer-NF5003E is promising for research of HIV infections.

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Mer-NF5003E

Mer-NF5003E Chemical Structure

CAS No. : 159121-98-9

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Description

Mer-NF5003E is a non-nucleoside reverse transcriptase inhibitor targeting HIV-1 reverse transcriptase (RT) (EC50=50 μM). Mer-NF5003E exhibits inhibitory activity against wild-type HIV-1 and multiple NNRTI-resistant strains (e.g., K103N, Y181C). Mer-NF5003E is promising for research of HIV infections[1].

Molecular Weight

388.50

Formula

C23H32O5

CAS No.
SMILES

C[C@@]12[C@@]3([C@@H](CC[C@@]1([H])C(C)([C@@H](CC2)O)C)C)OC4=C(C=O)C(CO)=CC(O)=C4C3

Structure Classification
Initial Source

Stachybotrys sp.

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Mer-NF5003E
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HY-N16422
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