N-Phenylbenzamide (Synonyms: N-Benzoylaniline)

Cat. No.: HY-W115609 Purity: 99.91%: Data Sheet
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N-Phenylbenzamide (N-Benzoylaniline) is a compound skeleton. N-Phenylbenzamide can be used for the researches of cancer and infection, such as enterovirus and cervical cancer.

For research use only. We do not sell to patients.

N-Phenylbenzamide Chemical Structure

CAS No. : 93-98-1

Size	Stock	Quantity
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
500 g	In-stock	Estimated Time of Arrival: December 31
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Description

N-Phenylbenzamide (N-Benzoylaniline) is a compound skeleton. N-Phenylbenzamide can be used for the researches of cancer and infection, such as enterovirus and cervical cancer^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	> 100 μM Compound: 9	Antiproliferative activity against human HCT116 cells after 72 hrs by cell counting kit analysis Antiproliferative activity against human HCT116 cells after 72 hrs by cell counting kit analysis	[PMID: 21664138]
HEK293	CC₅₀	> 100 μM Compound: 28	Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay	[PMID: 30392371]
MCF7	IC₅₀	> 100 μM Compound: 9	Antiproliferative activity against human MCF7 cells after 72 hrs by cell counting kit analysis Antiproliferative activity against human MCF7 cells after 72 hrs by cell counting kit analysis	[PMID: 21664138]
MDA-MB-231	IC₅₀	> 100 μM Compound: 9	Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by cell counting kit analysis Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by cell counting kit analysis	[PMID: 21664138]
SK-BR-3	IC₅₀	> 100 μM Compound: 9	Antiproliferative activity against human SK-BR-3 cells after 72 hrs by cell counting kit analysis Antiproliferative activity against human SK-BR-3 cells after 72 hrs by cell counting kit analysis	[PMID: 21664138]
SW480	IC₅₀	> 100 μM Compound: 9	Antiproliferative activity against human SW480 cells after 72 hrs by cell counting kit analysis Antiproliferative activity against human SW480 cells after 72 hrs by cell counting kit analysis	[PMID: 21664138]
SW-620	IC₅₀	> 100 μM Compound: 9	Antiproliferative activity against human SW620 cells after 72 hrs by cell counting kit analysis Antiproliferative activity against human SW620 cells after 72 hrs by cell counting kit analysis	[PMID: 21664138]

In Vitro

N-Phenylbenzamide (derivatives) shows anti-EV71 (Enterovirus 71) and anti-HCV (Hepatitis C virus) activity^[1].
N-Phenylbenzamide (3-Chloro-N-phenylbenzamide) shows anti-proliferative activity with an IC₅₀ of 22.4 μM in SiHa cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

197.24

Formula

C₁₃H₁₁NO

CAS No.

93-98-1

Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1=CC=CC=C1)C2=CC=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (507.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.0700 mL	25.3498 mL	50.6997 mL
5 mM	1.0140 mL	5.0700 mL	10.1399 mL
10 mM	0.5070 mL	2.5350 mL	5.0700 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.91%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (248 KB) HNMR (117 KB) RP-HPLC (177 KB)

Handling Instructions (2659 KB)

References

[1]. Jiang Z, et al. Synthesis and antiviral activity of a series of novel N-phenylbenzamide and N-phenylacetophenone compounds as anti-HCV and anti-EV71 agents. Acta Pharm Sin B. 2015 May;5(3):201-9. [Content Brief]

[2]. Theerachayanan T, et al. SYNTHESIS AND ANTI-CANCER ACTIVITY OF 3-CHLORO-N-PHENYLBENZAMIDE. Interprof J Health Sci. 2019 Dec. 20;17(2):72-9.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.0700 mL	25.3498 mL	50.6997 mL	126.7491 mL
	5 mM	1.0140 mL	5.0700 mL	10.1399 mL	25.3498 mL
	10 mM	0.5070 mL	2.5350 mL	5.0700 mL	12.6749 mL
	15 mM	0.3380 mL	1.6900 mL	3.3800 mL	8.4499 mL
	20 mM	0.2535 mL	1.2675 mL	2.5350 mL	6.3375 mL
	25 mM	0.2028 mL	1.0140 mL	2.0280 mL	5.0700 mL
	30 mM	0.1690 mL	0.8450 mL	1.6900 mL	4.2250 mL
	40 mM	0.1267 mL	0.6337 mL	1.2675 mL	3.1687 mL
	50 mM	0.1014 mL	0.5070 mL	1.0140 mL	2.5350 mL
	60 mM	0.0845 mL	0.4225 mL	0.8450 mL	2.1125 mL
	80 mM	0.0634 mL	0.3169 mL	0.6337 mL	1.5844 mL
	100 mM	0.0507 mL	0.2535 mL	0.5070 mL	1.2675 mL

N-Phenylbenzamide Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Phenylbenzamide93-98-1N-BenzoylanilineEnterovirusBiochemical Assay ReagentsRhinovirusHRVHRVsHEVHEVsEV71HCVSiHacervical cancerInhibitorinhibitorinhibit

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N-Phenylbenzamide (Synonyms: N-Benzoylaniline)

N-Phenylbenzamide Related Antibodies

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References

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N-Phenylbenzamide Related Antibodies

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