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  3. N3-PEG11-CH2CH2Br

N3-PEG11-CH2CH2Br is a PEG linker containing a bromine and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The bromine (Br) is a very good leaving group for nucleophilic substitution reactions.

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N3-PEG11-CH2CH2Br

N3-PEG11-CH2CH2Br Chemical Structure

CAS No. : 2098982-00-2

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Description

N3-PEG11-CH2CH2Br is a PEG linker containing a bromine and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The bromine (Br) is a very good leaving group for nucleophilic substitution reactions.

Molecular Weight

634.56

Formula

C24H48BrN3O11

CAS No.
Appearance

Viscous Liquid

Color

Colorless to light yellow

SMILES

BrCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (157.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5759 mL 7.8795 mL 15.7590 mL
5 mM 0.3152 mL 1.5759 mL 3.1518 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5759 mL 7.8795 mL 15.7590 mL 39.3974 mL
5 mM 0.3152 mL 1.5759 mL 3.1518 mL 7.8795 mL
10 mM 0.1576 mL 0.7879 mL 1.5759 mL 3.9397 mL
15 mM 0.1051 mL 0.5253 mL 1.0506 mL 2.6265 mL
20 mM 0.0788 mL 0.3940 mL 0.7879 mL 1.9699 mL
25 mM 0.0630 mL 0.3152 mL 0.6304 mL 1.5759 mL
30 mM 0.0525 mL 0.2626 mL 0.5253 mL 1.3132 mL
40 mM 0.0394 mL 0.1970 mL 0.3940 mL 0.9849 mL
50 mM 0.0315 mL 0.1576 mL 0.3152 mL 0.7879 mL
60 mM 0.0263 mL 0.1313 mL 0.2626 mL 0.6566 mL
80 mM 0.0197 mL 0.0985 mL 0.1970 mL 0.4925 mL
100 mM 0.0158 mL 0.0788 mL 0.1576 mL 0.3940 mL
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N3-PEG11-CH2CH2Br Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
N3-PEG11-CH2CH2Br
Cat. No.:
HY-W190881
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