Pyrazole-3-carboxylic acid

Name: Pyrazole-3-carboxylic acid
Brand: MedChemExpress
SKU: HY-W002328
Rating: 4.5 (1 reviews)

Cat. No.: HY-W002328 Purity: 99.97%: Data Sheet
COA

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Handling Instructions
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Pyrazole-3-carboxylic acid is an alternative anchoring group to carboxylic acid in phthalocyanine dyes. Pyrazole-3-carboxylic acid shows flexible coordination modes when coordinates with metal ions. Pyrazole-3-carboxylic acid can chelate to metal ions and form very stable complexes through its N and O atoms. Pyrazole-3-carboxylic acid can be used to synthesize derivatives that possess antibacterial, anti-inflammatory, ulcerogenic liability and antiproliferative activities.

For research use only. We do not sell to patients.

Pyrazole-3-carboxylic acid Chemical Structure

CAS No. : 1621-91-6

Size	Stock	Quantity
25 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

Pyrazole-3-carboxylic acid can be used to synthesize derivatives that possess antibacterial, anti-inflammatory, ulcerogenic liability and antiproliferative activities^[1]^[2]^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

112.09

Formula

C₄H₄N₂O₂

CAS No.

1621-91-6

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=NNC=C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (892.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	8.9216 mL	44.6078 mL	89.2156 mL
5 mM	1.7843 mL	8.9216 mL	17.8431 mL
10 mM	0.8922 mL	4.4608 mL	8.9216 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.97%

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Data Sheet (273 KB) SDS (392 KB)

COA (248 KB) HNMR (127 KB) RP-HPLC (230 KB)

Handling Instructions (2659 KB)

References

[1]. Burak Yıldız, et al., (2018) Pyrazole-3-carboxylic acid as a new anchoring group for phthalocyanine-sensitized solar cells, Solar Energy, Volume 174, Pages 527-536, ISSN 0038-092X.

[2]. Abdel-Hafez, el-S. M., et al., (2009). Design, synthesis and biological investigation of certain pyrazole-3-carboxylic acid derivatives as novel carriers for nitric oxide. Bioorganic & medicinal chemistry, 17(11), 3829–3837. [Content Brief]

[3]. Kasımoğulları, R., et al., Design, synthesis, characterization, and antiproliferative activity of novel pyrazole-3-carboxylic acid derivatives. Monatsh Chem 146, 1743–1749 (2015).

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	8.9216 mL	44.6078 mL	89.2156 mL	223.0390 mL
	5 mM	1.7843 mL	8.9216 mL	17.8431 mL	44.6078 mL
	10 mM	0.8922 mL	4.4608 mL	8.9216 mL	22.3039 mL
	15 mM	0.5948 mL	2.9739 mL	5.9477 mL	14.8693 mL
	20 mM	0.4461 mL	2.2304 mL	4.4608 mL	11.1520 mL
	25 mM	0.3569 mL	1.7843 mL	3.5686 mL	8.9216 mL
	30 mM	0.2974 mL	1.4869 mL	2.9739 mL	7.4346 mL
	40 mM	0.2230 mL	1.1152 mL	2.2304 mL	5.5760 mL
	50 mM	0.1784 mL	0.8922 mL	1.7843 mL	4.4608 mL
	60 mM	0.1487 mL	0.7435 mL	1.4869 mL	3.7173 mL
	80 mM	0.1115 mL	0.5576 mL	1.1152 mL	2.7880 mL
	100 mM	0.0892 mL	0.4461 mL	0.8922 mL	2.2304 mL