2. PROTAC Protein Tyrosine Kinase/RTK
  3. Target Protein Ligand-Linker Conjugates Src
  4. N-Deshydroxyethyl Dasatinib-C3-NH2

N-Deshydroxyethyl Dasatinib-C3-NH2  (Synonyms: N-Deshydroxyethyl BMS-354825-C3-NH2)

Cat. No.: HY-175193
Handling Instructions Technical Support

N-Deshydroxyethyl Dasatinib-C3-NH2 is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for LCK (HY-107447) and a PROTAC linker (HY-76667), which recruits E3 ligases. N-Deshydroxyethyl Dasatinib-C3-NH2 can be used for synthesis of PROTAC SJ11646 (HY-175281).

For research use only. We do not sell to patients.

N-Deshydroxyethyl Dasatinib-C3-NH2 Chemical Structure

N-Deshydroxyethyl Dasatinib-C3-NH2 Chemical Structure

CAS No. : 1430089-58-9

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N-Deshydroxyethyl Dasatinib-C3-NH2 Related Antibodies

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Lck Fyn Blk Hck Lyn Yes SRC-3

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Description

N-Deshydroxyethyl Dasatinib-C3-NH2 is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for LCK (HY-107447) and a PROTAC linker (HY-76667), which recruits E3 ligases. N-Deshydroxyethyl Dasatinib-C3-NH2 can be used for synthesis of PROTAC SJ11646 (HY-175281)[1][2].

IC50 & Target[2]

Lck

 

Molecular Weight

501.05

Formula

C23H29ClN8OS
CAS No.
SMILES

O=C(C1=CN=C(NC2=NC(C)=NC(N3CCN(CCCN)CC3)=C2)S1)NC4=C(C)C=CC=C4Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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N-Deshydroxyethyl Dasatinib-C3-NH2 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Deshydroxyethyl Dasatinib-C3-NH21430089-58-9N-Deshydroxyethyl BMS-354825-C3-NH2Target Protein Ligand-Linker ConjugatesSrcTarget Protein Ligand-Linker ConjugateLCKInhibitorinhibitorinhibit

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