Search Result

Results for "

thymidylate synthase,apoptosis,DNA synthesis

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA/RNA Synthesis (596) Thymidylate Synthase (44) 5 alpha Reductase (1) 5-HT Receptor (6) Acetolactate Synthase (ALS) (1) Acetyl-CoA Carboxylase (6) Acyltransferase (10) ADC Antibody (13) ADC Cytotoxin (78) ADC Linker (685) Adenosine Deaminase (3) Adenosine Kinase (1) Adenosine Receptor (2) Adenylate Cyclase (3) Adrenergic Receptor (10) Akt (10) Aldose Reductase (1) Amino Acid Derivatives (123) Aminoacyl-tRNA Synthetase (5) Aminopeptidase (1) AMPK (20) Amylases (2) Amyloid-β (4) Anaplastic lymphoma kinase (ALK) (2) Androgen Receptor (9) Angiotensin Receptor (9) Angiotensin-converting Enzyme (ACE) (1) ANGPTL (2) Antibiotic (383) Antibody-Drug Conjugates (ADCs) (1) Antifolate (25) AP-1 (2) Apolipoprotein (2) Apoptosis (275) Arenavirus (1) Arp2/3 Complex (2) Arrestin (1) Aryl Hydrocarbon Receptor (2) ASCT (1) Atg8/LC3 (2) ATM/ATR (2) ATP Citrate Lyase (3) ATP Synthase (11) Aurora Kinase (1) AUTACs (1) Autophagy (163) Bacterial (497) Bcl-2 Family (17) Bcr-Abl (2) Beta-lactamase (8) Biochemical Assay Reagents (1138) Bradykinin Receptor (4) Btk (6) c-Met/HGFR (1) c-Myc (4) Calcium Channel (19) CaMK (4) Cannabinoid Receptor (5) Carbonic Anhydrase (3) Casein Kinase (1) Caspase (21) CD1 (2) CDK (14) CETP (1) CFTR (4) Checkpoint Kinase (Chk) (1) Cholinesterase (ChE) (15) Claudin (1) CMV (3) Collagen (2) Complement System (1) COX (42) CRAC Channel (2) CRFR (1) CXCR (4) Cyclophilin (1) Cytochrome P450 (25) Dengue Virus (8) Deubiquitinase (1) Dihydroceramide Desaturase 1 (DES1) (1) Dihydrofolate reductase (DHFR) (6) Dihydroorotate Dehydrogenase (9) Dipeptidyl Peptidase (6) DNA Alkylator/Crosslinker (9) DNA Methyltransferase (2) DNA Stain (1) Dopamine Receptor (11) Dopamine β-hydroxylase (2) Drug Derivative (32) Drug Intermediate (344) Drug Isomer (2) Drug Metabolite (48) Drug-Linker Conjugates for ADC (93) Dystrophin (3) E1/E2/E3 Enzyme (3) E3 Ligase Ligand-Linker Conjugates (248) EBI2/GPR183 (1) EBV (1) EGFR (18) Endogenous Metabolite (457) Endoplasmic Reticulum Oxidoreductase 1 (ERO1) (2) Endothelin Receptor (1) Enterovirus (4) Epigenetic Reader Domain (22) ERK (8) Estrogen Receptor/ERR (16) Eukaryotic Initiation Factor (eIF) (2) Factor Xa (2) FAK (2) FAP (6) Farnesyl Transferase (2) Fatty Acid Synthase (FASN) (9) Ferrochelatase (1) Ferroptosis (10) Filovirus (1) FKBP (5) FLAP (2) Flavivirus (7) FLT3 (2) Fluorescent Dye (67) Folate Receptor (FR) (1) Free Fatty Acid Receptor (1) Fungal (90) FXR (3) GABA Receptor (5) Galectin (2) GCGR (1) GHR (4) GHSR (1) Gli (1) GLP Receptor (1) Glucocorticoid Receptor (4) Glucosylceramide Synthase (GCS) (1) GLUT (2) Glutaminase (1) Glutathione Peroxidase (2) Glycosidase (7) Glycosyltransferase (4) GlyT (3) GnRH Receptor (2) GPR35 (1) GSK-3 (2) Guanylate Cyclase (4) HBV (8) HCV (16) HDAC (8) Hedgehog (2) Heme Oxygenase (HO) (2) Herbicide (12) HIF/HIF Prolyl-Hydroxylase (23) Histamine Receptor (6) Histone Acetyltransferase (1) Histone Demethylase (4) Histone Methyltransferase (5) HIV (28) HIV Protease (1) HMG-CoA Reductase (HMGCR) (18) HPV (1) HSP (5) HSV (33) IFNAR (1) IGF-1R (2) iGluR (4) Imidazoline Receptor (3) IMPDH (1) Indoleamine 2,3-Dioxygenase (IDO) (1) Influenza Virus (17) Insecticide (12) Insulin Receptor (2) Integrin (2) Interleukin Related (27) IRAK (1) IRE1 (2) Isotope-Labeled Compounds (271) Itk (1) JAK (2) JNK (4) Keap1-Nrf2 (3) Kinesin (1) Lactate Dehydrogenase (2) LDLR (3) Leukotriene Receptor (15) Ligands for E3 Ligase (93) Ligands for Target Protein for PROTAC (139) Lipase (2) Lipocalin Family (1) Liposome (68) Lipoxygenase (15) LPL Receptor (2) LXR (3) LYTACs (3) MAP4K (1) MDM-2/p53 (8) MEK (2) Melanocortin Receptor (4) mGluR (3) MicroRNA (2) Microtubule/Tubulin (38) Mineralocorticoid Receptor (3) Mitochondrial Metabolism (10) Mitophagy (11) Mitosis (1) MMP (7) MNK (1) Molecular Glues (1) Monoamine Oxidase (10) Mps1 (2) mTOR (8) Na+/K+ ATPase (2) nAChR (1) NADPH Oxidase (1) NAMPT (2) Necroptosis (10) NEDD8-activating Enzyme (2) NEKs (1) Neurokinin Receptor (1) Neuropeptide FF Receptor (1) Neuropeptide Y Receptor (2) NF-κB (20) NO Synthase (27) NOD-like Receptor (NLR) (3) Notch (1) Nuclear Factor of activated T Cells (NFAT) (2) Nuclear Hormone Receptor 4A/NR4A (1) Nucleoside Antimetabolite/Analog (1149) OGT (1) Opioid Receptor (2) Orphan Receptor (1) Orthopoxvirus (26) Oxidative Phosphorylation (10) P-glycoprotein (2) P2Y Receptor (1) p38 MAPK (17) p62 (2) Parasite (88) PARP (5) PCSK9 (5) PD-1/PD-L1 (6) PDGFR (2) PDI (2) Penicillin-binding protein (PBP) (11) PEPCK (1) Peptide-Drug Conjugates (PDCs) (1) PERK (4) PGC-1α (1) PGE synthase (13) Phosphatase (4) Phosphodiesterase (PDE) (2) Phosphoglycerate Dehydrogenase (PHGDH) (3) Phospholipase (6) Phosphorylase (1) Photosensitizer (2) Photosystem II (1) Phytohormone (2) PI3K (11) PIN1 (2) PKA (4) PKC (5) Platelet-activating Factor Receptor (PAFR) (4) Polo-like Kinase (PLK) (1) Potassium Channel (14) PPAR (17) Prion Protein (1) Prolyl Endopeptidase (PREP) (1) Prostaglandin Receptor (19) PROTAC Linkers (2907) PROTAC-Linker Conjugates for PAC (1) PROTACs (8) Protease Activated Receptor (PAR) (4) Proteasome (5) PSMA (10) Pyroptosis (2) Pyruvate Carboxylase (PC) (1) Radionuclide-Drug Conjugates (RDCs) (44) Raf (4) Ras (6) Reactive Oxygen Species (60) Reference Standards (35) Renin (1) RET (2) Reverse Transcriptase (8) Ribosomal S6 Kinase (RSK) (1) RSV (3) SARS-CoV (13) Ser/Thr Protease (5) Serotonin Transporter (2) SHMT (1) SHP2 (1) Sigma Receptor (1) Small Interfering RNA (siRNA) (8) SOD (5) Sodium Channel (8) Somatostatin Receptor (10) SOS1 (7) Src (3) STAT (7) STING (7) Survivin (1) SWI/SNF Complex (2) TAM Receptor (2) Target Protein Ligand-Linker Conjugates (25) Tau Protein (2) Telomerase (1) TGF-beta/Smad (9) TGF-β Receptor (1) Thrombin (1) Tie (1) TMV (1) TNF Receptor (20) Toll-like Receptor (TLR) (7) Topoisomerase (63) Transmembrane Glycoprotein (2) Transthyretin (TTR) (2) TROP2 (1) TRP Channel (8) TrxR (1) Tryptophan Hydroxylase (2) Tyrosinase (18) Tyrosine Hydroxylase (1) VD/VDR (3) VEGFR (2) Virus Protease (7) WDR5 (3) Xanthine Oxidase (1) YAP (1) α-synuclein (4) β-glucuronidase (1)
By Research Areas:	Cancer (5499) Cardiovascular Disease (144) Endocrinology (54) Infection (793) Inflammation/Immunology (365) Metabolic Disease (364) Neurological Disease (234)
Click Chemistry:	ADC Synthesis (233) TCO (61) Labeling and Fluorescence Imaging (1) DBCO (143) PROTAC Synthesis (785) Azide (581) BCN (59) Tetrazine (76) Alkynes (314)
Oligonucleotides:	A (151) C (83) Cosolvents (1) G (93) I1 (1) I (35) Phospholipids (8) siRNA drugs (8) Cap Analogs (19) Antisense Oligonucleotides (23) siRNAs (8) pH Modifiers (1) Fluorescent Lipids (2) T (26) Pegylated Lipids (38) U (328) Cationic Lipids (9) Polymers (7) Nucleosides and their Analogs (871) Nucleoside Phosphoramidites (132) Suspending Agents (1) Solubilizing Agents (1) Freeze-drying Protective Agents (2) Bases (1) Cholesterol (2) Nucleotides and their Analogs (33) Emulsifiers (1)

9102

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

1088

Biochemical Assay Reagents

269

Peptides

MCE Kits

Inhibitory Antibodies

588

Natural
Products

Recombinant Proteins

349

Isotope-Labeled Compounds

Antibodies

1210

Click Chemistry

1154

Oligonucleotides

Targets Recommended: Thymidylate Synthase DNA/RNA Synthesis

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W011142

2'-Deoxyuridine 5'-monophosphate disodium dUMP disodium	Endogenous Metabolite	Infection Metabolic Disease
2'-Deoxyuridine 5'-monophosphate (dUMP) disodium is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .

HY-144868

*Glutathione synthesis-IN-1*	Others	Metabolic Disease
Glutathione synthesis-IN-1 (DC-1) is a glutathione synthesis inhibitor .

HY-103396

Trimetrexate glucuronate 2 Publications Verification CI-898 glucuronate	Antifolate Bacterial	Infection Cancer
Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia .

HY-W394006

2'-Deoxyuridine 5'-monophosphate dUMP	Endogenous Metabolite	Infection Metabolic Disease
2'-Deoxyuridine 5'-monophosphate (dUMP) is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .

HY-149849

TS-IN-2	Thymidylate Synthase	Cancer
TS-IN-2 (compound 17) is a thymidylate synthase (TS) inhibitor with an IC₅₀ of 0.81 μM. TS-IN-2 induces cancer cell *apoptosis* and cell cycle arrest in S phase, and also inhibit DNA synthesis, resulting in DNA damage .

HY-157045

*ATP Synthesis-IN-1*	ATP Synthase	Infection
ATP Synthesis-IN-1 (Compound 4), quinoline derivative, is a potent inhibitor of PA ATP synthesis activity. ATP Synthesis-IN-1 has PA ATP synthesis inhibition with IC₅₀ value of 11.1μg/mL. ATP Synthesis-IN-1 also has antibacterial activity. ATP Synthesis-IN-1 can be used for the research of drug-resistant PA infection .

HY-122795

Vanoxonin	Thymidylate Synthase	Others
Vanoxonin is an inhibitor of **thymidylate synthase** found in Saccharopolyspora hirsuta with an IC₅₀ value of 0.7 μg/mL .

HY-137611A

α,β-MTDP trisodium	DNA/RNA Synthesis	Cancer
α,β-MTDP trisodium, a thymidylate analog, is a thymidine kinase inhibitor with a K_i of 23 µM .

HY-103396R

Trimetrexate glucuronate (Standard) CI-898 glucuronate (Standard)	Antifolate Bacterial	Infection Cancer
Trimetrexate (glucuronate) (Standard) is the analytical standard of Trimetrexate (glucuronate). This product is intended for research and analytical applications. Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia .

HY-157046

*ATP Synthesis-IN-2*	Bacterial ATP Synthase	Infection
ATP Synthesis-IN-2 (Compound 5) is an antibacterial compound. ATP Synthesis-IN-2 is a potent ATP synthesis activity inhibitor with IC₅₀ against Pseudomonas aeruginosa (PA) Value of 0.7 μg/mL .

HY-149736

*ATP Synthesis-IN-3*	PKA ATP Synthase	Cardiovascular Disease
ATP Synthesis-IN-3 (compound 31) is an ATP hydrolysis inhibitor with protective effects during myocardial ischemia. ATP Synthesis-IN-3 can increase the ATP content of ischemic cardiomyocytes, increase the phosphorylation of PKA and phospholamban, and inhibit ischemia-induced apoptosis .

HY-13728B

(Rac)-Plevitrexed (Rac)-ZD 9331; (Rac)-BGC9331	Thymidylate Synthase	Cancer
(Rac)-Plevitrexed ((Rac)-ZD 9331; (Rac)-BGC9331)?is a racemate of Plevitrexed. Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor. (Rac)-Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-13728A

(R)-Plevitrexed (R)-ZD 9331; (R)-BGC9331	Biochemical Assay Reagents	Cancer
(R)-Plevitrexed ((R)-ZD 9331; (R)-BGC9331) is a less active enantiomer of Plevitrexed . Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor . (R)-Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-16110

Tegafur-Uracil UFT; BMS-200604	Thymidylate Synthase	Cancer
Tegafur-Uracil (UFT; BMS-200604) is an effective oral chemotherapy drug based on fluoropyrimidine. Tegafur-Uracil inhibits **thymidylate synthase**. Tegafur-Uracil can be used in combination with leucovorin (LV) and polysaccharide K (PSK) for research on solid tumors .

HY-162698

JMF4073	Thymidylate Synthase	Cancer
JMF4073 is a thymidylate (TMP) and cytidylate (CMP) kinases inhibitor with IC₅₀s of 0.16 μM and 0.17 μM, respectively. JMF4073 eliminates wild-type (WT)-Bcr-Abl-transformed myeloid cells in vitro and in vivo .

HY-W142014

N,O-Didansyl-L-tyrosine cyclohexylammonium	Thymidylate Synthase	Cancer
N,O-Didansyl-L-tyrosine cyclohexylammonium is a potent selective thymidylate synthase (TS) inhibitor, acts on TS of Escherichia coli, Lactobacillus casei and human with the IC₅₀ values of 5.0, 3.4 and 119 μM, respectively .

HY-121256

Chlorasquin	Thymidylate Synthase Antifolate Dihydrofolate reductase (DHFR)	Others
Chlorasquin inhibits thymidylate synthetase with an approximate K_i value of 4.9 μM. Chlorasquin is also a folate antagonist, testing the Methotrexate (HY-14519) effect. Chlorasquin binds tighter to dihydrofolate reductase at alkaline pH than does Methotrexate, which is promising for research of antipsoriatic agents .

HY-143452

MtTMPK-IN-4	Tyrosinase Bacterial	Inflammation/Immunology
MtTMPK-IN-4 (compound 2), a para-piperidine, is a potent *mycobacterium tuberculosis thymidylate* kinase (MtTMPK) inhibitor with an IC₅₀ of 6.1 μM. MtTMPK-IN-4 is a potent tyrosinase** inhibitor. MtTMPK-IN-4 is a potent antibacterial agent .

HY-106168

Thymectacin NB1011	Thymidylate Synthase	Cancer
Thymectacin (NB1011) is an agent selectively targeting tumor cells that have a high expression of thymidylate synthase (TS). Thymectacin is an aryloxy phosphoramidate derivative of BVdU (brivudin) .

HY-129870

Diazoketone methotrexate	DNA/RNA Synthesis	Cancer
Diazoketone methotrexate, an analog of methotrexate, is an antitumor agent. Diazoketone methotrexate inhibits cell growth and inhibits synthesis of thymidylate .

HY-16478

Trifluridine/tipiracil hydrochloride mixture 1 Publications Verification TAS-102; FTD/TPI	Nucleoside Antimetabolite/Analog Thymidylate Synthase	Cancer
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent. The composition of Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a 1:0.5 mixture (on a molar basis) of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). Trifluridine/tipiracil hydrochloride mixture (TAS-102) shows the antitumor activity mainly via the inhibition of thymidylate synthase (TS) and incorporation into DNA .

HY-W013068

DMT-dT Phosphoramidite	DNA/RNA Synthesis	Others
DMT-dT Phosphoramidite is typically used in the synthesis of DNA .

HY-W008849

DMT-dC(bz) Phosphoramidite	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Others
DMT-dC(bz) Phosphoramidite is typically used in the synthesis of DNA .

HY-W013059

DMT-dA(bz) Phosphoramidite DA-CE phosphoramidite	DNA/RNA Synthesis	Others
DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA .

HY-W008848

DMT-dG(ib) Phosphoramidite	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog	Others
DMT-dG(ib) Phosphoramidite is typically used in the synthesis of DNA .

HY-132136

DMT-dU-CE Phosphoramidite	DNA/RNA Synthesis	Others
DMT-dU-CE Phosphoramidite is a nucleoside molecule that can be used in DNA synthesis and DNA sequencing .

HY-154508

FdUMP triethylammonium 2’-Deoxy-5-Fluorouridine 5’-phosphate triethylammonium	Nucleoside Antimetabolite/Analog Thymidylate Synthase	Cancer
FdUMP triethylammonium is the intracellular active form of 5-fluorouracil (5-FU). 5-FU is converted to FdUMP after being transported into the cell by various enzymes. FdUMP forms a ternary complex with thymidylate synthase and its cofactor 5,10-methylene tetrahydrofolate, inhibiting the activity of thymidylate synthase, which in turn leads to the suppression of DNA synthesis.

HY-145975A

m7Gpppm6AmpG (ammonium) solution (100mM)	DNA/RNA Synthesis	Others
m7Gpppm6AmpG ammonium solution (100mM) is a trinucleotide mRNA 5’ cap analogs. m7Gpppm6AmpG ammonium can be used for RNA synthesis in vitro .

HY-101400

Deoxycytidine triphosphate 1 Publications Verification dCTP; 2′-Deoxycytidine-5′-triphosphate	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .

HY-156122

DHFR-IN-8	Dihydrofolate reductase (DHFR) Bacterial	Infection
DHFR-IN-8 (compound 6r) is a dihydrofolate reductase (DHFR) inhibitor that affects purine and thymidylate biosynthesis in cell proliferation and growth. DHFR-IN-8 inhibits methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 (IC₅₀=15.6 ng/mL) in mouse models of systemic infection and thigh infection .

HY-101400A

Deoxycytidine triphosphate (trisodium) solution (100mM) 1 Publications Verification dCTP (trisodium) solution (100mM); 2′-Deoxycytidine-5′-triphosphate (trisodium) solution (100mM)	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .

HY-W013059R

DMT-dA(bz) Phosphoramidite (Standard)	DNA/RNA Synthesis	Others
DMT-dA(bz) Phosphoramidite (Standard) is the analytical standard of DMT-dA(bz) Phosphoramidite. This product is intended for research and analytical applications. DMT-dA(bz) Phosphoramidite is a phosphoramide monomer for the synthesis of oligonucleotides (ONs) through formation of DNA dimers and trimers via mechanochemistry .

HY-19157

Metesind glucuronate AG 331	Thymidylate Synthase	Cancer
Metesind glucuronate (AG 331) is an inhibitor for **thymidylate synthase with K_i** of 1.2 nM. Metesind glucuronate inhibits the DNA synthesis and thus inhibits the cell viability of cancer cells with IC₅₀ of 0.4-0.9 μM .

HY-W048480

7-Iodo-2',3'-dideoxy-7-deazaadenosine	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Others
7-Iodo-2',3'-dideoxy-7-deazaadenosine is a dideoxynucleoside that can be used in DNA synthesis and sequencing reactions .

HY-W048479

7-Iodo-2',3'-dideoxy-7-deaza-guanosine 1 Publications Verification	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis	Others
7-Iodo-2',3'-dideoxy-7-deaza-guanosine is a dideoxynucleoside that can be used in DNA synthesis and sequencing reactions .

HY-D0186S5

2'-Deoxyuridine-d	Isotope-Labeled Compounds Endogenous Metabolite	Infection
2'-Deoxyuridine-d is the deuterium labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud <

HY-10822

Idetrexed BGC 945; ONX-0801	Thymidylate Synthase	Others
Idetrexed is a **thymidylate synthase** inhibitor specifically transported into alpha-folate receptor (alpha-FR)-overexpressing tumors. BGC 945 inhibited thymidylate synthase with a K_i of 1.2 nmol/L .

HY-146239

EGFR/HER2/TS-IN-2	EGFR Thymidylate Synthase	Cancer
EGFR/HER2/TS-IN-2 (compound 17) is a potent EGFR/HER2 and TS (Thymidylate synthase) inhibitor, with IC₅₀ values of 0.173, 0.125, and 1.12 μM, respectively. EGFR/HER2/TS-IN-2 shows cytotoxic activity against MDA-MB-231 cancer cell lines, with an IC₅₀ of 1.69 µM .

HY-D0186S4

2'-Deoxyuridine-d2	Isotope-Labeled Compounds Endogenous Metabolite	Infection
2'-Deoxyuridine-d₂ is the deuterium labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud

HY-W048492

7-Iodo-7-deaza-2'-deoxyguanosine 7-Deaza-7-Iodo-2'-deoxyguanosine	DNA/RNA Synthesis	Others
7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a deoxyguanosine derivative that can be used in DNA synthesis and sequencing reactions .

HY-D0186S8

2'-Deoxyuridine-d2-1	Endogenous Metabolite	Infection
2'-Deoxyuridine-d₂-1 is the deuterium labeled 2'-Deoxyuridine . 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine .

HY-10821

Raltitrexed 5+ Cited Publications ZD1694; D1694; ICI-D1694	Thymidylate Synthase Nucleoside Antimetabolite/Analog	Cancer
Raltitrexed is an antimetabolite agent used in chemotherapy, acting by inhibiting **thymidylate synthase**.

HY-D0186S3

2'-Deoxyuridine-5′-13C	Isotope-Labeled Compounds Endogenous Metabolite	Infection
2'-Deoxyuridine-5′- ¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-D0186S2

2'-Deoxyuridine-3′-13C	Isotope-Labeled Compounds Endogenous Metabolite	Infection
2'-Deoxyuridine-3′- ¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-D0186S1

2'-Deoxyuridine-2′-13C	Isotope-Labeled Compounds Endogenous Metabolite	Infection
2'-Deoxyuridine-2′- ¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-D0186S

2'-Deoxyuridine-1′-13C	Isotope-Labeled Compounds Endogenous Metabolite	Infection
2'-Deoxyuridine-1′- ¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-158622

AcycloATP sodium	Biochemical Assay Reagents DNA/RNA Synthesis	Others
AcycloATP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .

HY-W784575A

dGTPαS sodium 2'-Deoxyguanosine-5'-O-(α-thio)triphosphate sodium	Biochemical Assay Reagents DNA/RNA Synthesis	Others
dGTPαS sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .

HY-W784574A

dCTPαS sodium 2'-Deoxycytidine-5'-O-1-thiotriphosphate (sodium)	Biochemical Assay Reagents DNA/RNA Synthesis	Others
dCTPαS sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .

HY-158707

dTTPαS sodium	Biochemical Assay Reagents DNA/RNA Synthesis	Others
dTTPαS sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W011142

2'-Deoxyuridine 5'-monophosphate disodium dUMP disodium	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2'-Deoxyuridine 5'-monophosphate (dUMP) disodium is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .

HY-101400

Deoxycytidine triphosphate 1 Publications Verification dCTP; 2′-Deoxycytidine-5′-triphosphate	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Pyridine Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite
Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .

HY-101400A

Deoxycytidine triphosphate (trisodium) solution (100mM) 1 Publications Verification dCTP (trisodium) solution (100mM); 2′-Deoxycytidine-5′-triphosphate (trisodium) solution (100mM)	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite
Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .

HY-90006

5-Fluorouracil 220+ Cited Publications 5-FU	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Nucleoside Antimetabolite/Analog HIV Apoptosis Endogenous Metabolite
5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces *apoptosis* and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .

HY-W019724

2,2-Dihydroxyacetic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Drug Intermediate
2,2-Dihydroxyacetic acid is a key intermediate used in the synthesis of 3-aminocoumarone derivatives, which exhibit significant activity in chemiluminescence reactions and can be used for detecting hydrogen peroxide and evaluating urease activity .

HY-N6069

Raspberry ketone glucoside 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Rosaceae Plants Rubus corchorifolius Linn. f. Disease Research Fields Inflammation/Immunology	Others
Raspberry ketone glucoside is a natural product in raspberry fruit. Raspberry ketone glucosidev has the inhibitory effect on the melanin synthesis .

HY-122795

Vanoxonin	Structural Classification Natural Products Microorganisms Source classification	Thymidylate Synthase
Vanoxonin is an inhibitor of **thymidylate synthase** found in Saccharopolyspora hirsuta with an IC₅₀ value of 0.7 μg/mL .

HY-N14161

Diazaquinomycin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Thymidylate Synthase Apoptosis
Diazaquinomycin A (DAQA), a diaza-anthracene antibiotic, is a **thymidylate synthase** inhibitor. Diazaquinomycin A (DAQA) induces DNA damage, cell cycle arrest, and apoptosis through cleaved-PARP .

HY-113400

Cytidine 5'-diphosphate Cytidine diphosphate	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cytidine 5'-diphosphate (Cytidine diphosphate) is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-W008940

Cytidine 5'-diphosphate disodium salt Cytidine diphosphate disodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-131576

Thymidine 5′-diphosphate dTDP	Infection Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Thymidine 5′-diphosphate (dTDP) is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg ²⁺. Thymidine 5′-diphosphate is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .

HY-131576A

Thymidine 5′-diphosphate sodium dTDP sodium	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg ²⁺. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .

HY-90006R

5-Fluorouracil (Standard) 5-FU (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Reference Standards Nucleoside Antimetabolite/Analog HIV Apoptosis Endogenous Metabolite
5-Fluorouracil (Standard) is the analytical standard of 5-Fluorouracil. This product is intended for research and analytical applications. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces *apoptosis* and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .

HY-113037C

Farnesyl pyrophosphate ammonium Farnesyl diphosphate ammonium	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	TRP Channel Endogenous Metabolite
Farnesyl pyrophosphate ammonium salt, a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. Farnesyl pyrophosphate ammonium salt is a TRPM2 (TRP Channel) agonist, and activates TRPM2 opening for ion influx. Farnesyl pyrophosphate ammonium salt is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis .

HY-138615

Deoxythymidine-5'-triphosphate dTTP	Infection Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite
Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA .

HY-N14769

2-Hydroxyaclacinomycin B	Quinones Structural Classification Microorganisms Anthraquinones Source classification	Bacterial
2-Hydroxyaclacinomycin B is an anthracycline antibiotic. 2-Hydroxyaclacinomycin B can be found in Strptomyces galilaeus A-862 (FERM BP-45). 2-Hydroxyaclacinomycin B inhibits RNA synthesis and has anti-tumor activity .

HY-17561

G-418 disulfate 35+ Cited Publications Geneticin sulfate; Antibiotic G-418 sulfate	Structural Classification Antifungal Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Disease Research Fields	Bacterial Antibiotic
G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells .

HY-W008940R

Cytidine 5'-diphosphate disodium salt (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Cytidine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-W020033

Lanosterol 3 Publications Verification	Triterpenes Structural Classification Human Gut Microbiota Metabolites Terpenoids Source classification Endogenous metabolite	Endogenous Metabolite
Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol suppresses the aggregation and cytotoxicity of misfolded proteins linked with neurodegenerative diseases .

HY-N15176

Bisucaberin	Structural Classification Natural Products Microorganisms Source classification	DNA/RNA Synthesis
Bisucaberin is a natural siderophore, is a DNA synthesis inhibitor. Bisucaberin shows cytostasis for tumor cells. Bisucaberin sensitizes tumor cells to macrophage-mediated cytolysis .

HY-W010382

Oxaloacetic acid 2-Oxosuccinic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Other disease Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Reactive Oxygen Species
Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function .

HY-W020033R

Lanosterol (Standard)	Triterpenes Structural Classification Human Gut Microbiota Metabolites Microorganisms Terpenoids Source classification Endogenous metabolite	Endogenous Metabolite
Lanosterol (Standard) is the analytical standard of Lanosterol. This product is intended for research and analytical applications. Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol suppresses the aggregation and cytotoxicity of misfolded proteins linked with neurodegenerative diseases[1][2].

HY-17561R

G-418 disulfate (Standard) Geneticin sulfate (Standard); Antibiotic G-418 sulfate (Standard)	Structural Classification Plant Cell Culture Microorganisms Antifungal Antibiotics Resistance Selection Source classification Antibacterial Disease Research Other Antibiotics	Reference Standards Bacterial Antibiotic
G-418 (disulfate) (Standard) is the analytical standard of G-418 (disulfate). This product is intended for research and analytical applications. G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells[1].

HY-W010382R

Oxaloacetic acid (standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Other disease Ketones, Aldehydes, Acids Source classification Disease markers Endogenous metabolite	Endogenous Metabolite Reactive Oxygen Species
Oxaloacetic acid (Standard) is the analytical standard of Oxaloacetic acid. This product is intended for research and analytical applications. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function .

HY-W091784

3'-O-Methylguanosine	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite Orthopoxvirus Nucleoside Antimetabolite/Analog
3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator. 3'-O-methylguanosine can inhibit early virus-specific RNA synthesis .

HY-D0186

2'-Deoxyuridine 1 Publications Verification	Infection Structural Classification Natural Products Immune System Disorder Microorganisms Classification of Application Fields Source classification Disease markers Endogenous metabolite Disease Research Fields	Endogenous Metabolite Thymidylate Synthase
2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) .

HY-N1639

1-Decarboxy-3-oxo-ceanothic acid DOCA	Triterpenes Structural Classification Animals Terpenoids Source classification	Apoptosis DNA/RNA Synthesis
1-Decarboxy-3-oxo-ceanothic acid is an anticancer agent. 1-Decarboxy-3-oxo-ceanothic acid inhibits DNA synthesis. 1-Decarboxy-3-oxo-ceanothic acid induces *Apoptosis* .

HY-N3925

Ganoderol A	Triterpenes Classification of Application Fields Terpenoids Source classification Polyporaceae Metabolic Disease Plants Disease Research Fields Inflammation/Immunology	Bacterial
Ganoderol A is a terpenoid extracted from Ganoderma lucidum with antimicrobial activities. Ganoderol A inhibits cholesterol synthesis pathway and has significant anti-inflammatory activity and protection against ultraviolet A (UVA) damage .

HY-N3810

ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid	Structural Classification Terpenoids Source classification Pteridaceae Diterpenoids Plants Pteris semipinnata L. Sp.	Tyrosinase
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is an anti-melanin synthesis tyrosinase inhibitor, which can be isolated from Pteris fern. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid regulates the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF). The 11α-OH, 15-oxo and 16-en moieties of ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid are key fragments that inhibit melanin synthesis. The 19-COOH moiety has been implicated in the inhibition of cytotoxicity associated with 11α-OH KA and related compounds .

HY-N1797

3,7-Di-O-methylducheside A	Psittacanthus cucullaris (Lam.) G.Don Structural Classification Natural Products Source classification Plants Loranthaceae	Others
3, 7-di-o-methylducheside A (Compound 2) is a ethyl acetate extract of Psittacanthus cucullaris. 3, 7-di-o-methylducheside A stimulates the formation of glycosaminoglycan chains. 3, 7-di-o-methylducheside A can be used to study the rate of glycosaminoglycan synthesis .

HY-14520A

(6S)-Tetrahydrofolic acid (6S)-5,6,7,8-Tetrahydrofolic acid	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
(6S)-Tetrahydrofolic acid is 1000-fold more active than the (6R) form at promoting the binding of fluorodeoxyuridylate to thymidylate synthase and 600-fold more active as a growth factor of P. cerevisiae. (6S)-Tetrahydrofolic acid also has a low affinity and high dissociation rate for folate-binding protein .

HY-N2078

Yamogenin Neodiosgenin	Structural Classification other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields Steroids	LXR
Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin (Neodiosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin (Neodiosgenin) inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes .

HY-N8495

4'-Hydroxyflavanone	Flavonoids Monophenols Microorganisms Classification of Application Fields Flavonones Source classification Phenols Metabolic Disease Disease Research Fields	Others
4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis. 4'-Hydroxyflavanone is a synthetic analogue of flavanone, has potential for hepatic steatosis and dyslipidemia research .

HY-B0470

Neomycin sulfate 40+ Cited Publications	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields	Bacterial Antibiotic Phospholipase
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis .

HY-N7517

Adenosine 5′-monophosphoramidate sodium	Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Nucleoside Antimetabolite/Analog
Adenosine 5′-monophosphoramidate sodium is an adenosine derivative and can be used as an intermediate for nucleotide synthesis. Adenosine 5′-monophosphoramidate has a significant effect on the accumulation of cyclic AMP .

HY-W013715A

Deoxythymidine-5'-triphosphate (trisodium) solution (100mM) dTTP (trisodium) solution (100mM)	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite
Deoxythymidine-5'-triphosphate (dTTP) trisodium solution (100mM) is one of the four nucleoside triphosphates used in the synthesis of DNA .

HY-N10094

Maculosidine	Structural Classification Alkaloids Source classification Rutaceae Quinoline Alkaloids Plants Balfourodendron riedelianum (Engl.) Engl.	Others
Maculosidine is a furoquinoline alkaloid that can be isolated from Balfourodendron riedelianum. Maculosidine inhibits ATP synthesis, basal, phosphorylating and uncoupled electron transport in plants. Maculosidine inhibits Hill reaction on spinach chloroplasts .

HY-134636

PAPA NONOate	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite
PAPA NONOate is a NO donor with a NO release half-life of 77 min (22-25°C). PAPA NONOate may represent a potential research for impaired wound healing in diabetes by increasing the rate of collagen synthesis at the wound site .

HY-18572

2,4-D 2,4-Dichlorophenoxyacetic acid	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields Biological Pesticide Research Agricultural Research	DNA/RNA Synthesis Apoptosis
2,4-D (2, 4-dichlorophenoxyacetic acid) is a selective herbicide that can be orally active for the control of broad-leaved weeds. 2,4-D can induce *apoptosis. 2,4-D inhibits DNA* and protein synthesis, thereby preventing normal plant growth and development .

HY-N2078R

Yamogenin (Standard)	Structural Classification other families Source classification Plants Steroids	LXR
Yamogenin (Standard) is the analytical standard of Yamogenin. This product is intended for research and analytical applications. Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin (Neodiosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin (Neodiosgenin) inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes .

HY-N6961

Lapachol 2 Publications Verification	Infection Quinones Structural Classification Classification of Application Fields Tabebuia avellanedae Bignoniaceae Plants Naphthalene Quinones Inflammation/Immunology Disease Research Fields	Dihydroorotate Dehydrogenase DNA/RNA Synthesis Parasite
Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity .

HY-B0220

Erythromycin 15+ Cited Publications	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields	Bacterial Antibiotic DNA/RNA Synthesis
Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid ^[1][2]. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research ^[3][4].

HY-129337

Reveromycin A	Infection Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields Other Antibiotics	Antibiotic Fungal Apoptosis
Reveromycin A, a benzoquinoid antibiotic isolated from the genus Streptomyces, is a selective inhibitor of protein synthesis in eukaryotic cells. Reveromycin A inhibits bone resorption by inducing *apoptosis* specifically in osteoclasts. Reveromycin A has antiproliferative activity against tumor cell lines and antifungal activity .

HY-B0470R

Neomycin (sulfate) (Standard)	Structural Classification Microorganisms Antibiotics Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Anticancer Other Antibiotics	Bacterial Antibiotic Phospholipase
Neomycin (sulfate) (Standard) is the analytical standard of Neomycin (sulfate). This product is intended for research and analytical applications. Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis .

HY-W267446

6-Methoxy-4-methylcoumarin	Structural Classification Citrus × aurantium Linnaeus Source classification Rutaceae Coumarins Phenylpropanoids Plants Daphniphyllum macropodum Miq.	Melanocortin Receptor GSK-3
6-Methoxy-4-methylcoumarin is a 4-methylcoumarin derivative with an antitumor activity. 6-Methoxy-4-methylcoumarin activates melanin synthesis in B16F10 melanoma cells. 6-Methoxy-4-methylcoumarin is a pigmentation stimulator, and can be used for the study of skin conditions such as vitiligo .

HY-B0220R

Erythromycin (Standard)	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields	Bacterial Antibiotic DNA/RNA Synthesis
Erythromycin (Standard) is the analytical standard of Erythromycin. This product is intended for research and analytical applications. Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid . Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research .

HY-N6961R

Lapachol (Standard)	Quinones Structural Classification Tabebuia avellanedae Bignoniaceae Plants Naphthalene Quinones	Dihydroorotate Dehydrogenase DNA/RNA Synthesis Parasite
Lapachol (Standard) is the analytical standard of Lapachol. This product is intended for research and analytical applications. Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity .

HY-N8495R

4'-Hydroxyflavanone (Standard)	Monophenols Flavonoids Microorganisms Flavonones Source classification Phenols	Fatty Acid Synthase (FASN)
4'-Hydroxyflavanone (Standard) is the analytical standard of 4'-Hydroxyflavanone. This product is intended for research and analytical applications. 4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis. 4'-Hydroxyflavanone is a synthetic analogue of flavanone, has potential for hepatic steatosis and dyslipidemia research[1].

HY-N3716

Dehydroglyasperin D	Structural Classification Leguminosae Source classification Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch.	Aldose Reductase COX
Dehydroglyasperin D inhibits rat and human Aldose Reductase (AR) (IC₅₀: 62.4 μM and 176.2 μM respectively). Dehydroglyasperin D has anti-obesity, antioxidant effects. Dehydroglyasperin D shows anti-inflammatory activity by inhibiting COX-2 expression and the MLK3 signaling pathway. Dehydroglyasperin D also inhibits melanin synthesis. Dehydroglyasperin D is a prenylated flavonoid that can be isolated from Glycyrrhiza uralensi .

HY-B0275

Oxytetracycline 5 Publications Verification	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Endogenous metabolite Other Antibiotics Plant agriculture research Infection Monophenols Microorganisms Antibiotics Resistance Selection Animal Husbandry Phenols Disease Research Fields	Bacterial HSV Endogenous Metabolite Antibiotic
Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity .

Cat. No.	Product Name	Chemical Structure

HY-D0186S7

2'-Deoxyuridine-13C,15N2
2'-Deoxyuridine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled 2'-Deoxyuridine . 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine .

HY-90006S

5-Fluorouracil-d1
5-Fluorouracil-d is the deuterium labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .

HY-D0186S5

2'-Deoxyuridine-d
2'-Deoxyuridine-d is the deuterium labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud <

HY-D0186S4

2'-Deoxyuridine-d2
2'-Deoxyuridine-d₂ is the deuterium labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud

HY-D0186S8

2'-Deoxyuridine-d2-1
2'-Deoxyuridine-d₂-1 is the deuterium labeled 2'-Deoxyuridine . 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine .

HY-D0186S3

2'-Deoxyuridine-5′-13C
2'-Deoxyuridine-5′- ¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-D0186S2

2'-Deoxyuridine-3′-13C
2'-Deoxyuridine-3′- ¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-D0186S1

2'-Deoxyuridine-2′-13C
2'-Deoxyuridine-2′- ¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-D0186S

2'-Deoxyuridine-1′-13C
2'-Deoxyuridine-1′- ¹³C is the ¹³C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

HY-A0061S

Trifluridine-13C,15N2
Trifluridine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Trifluridine . Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity .

HY-W013068S3

DMT-dT Phosphoramidite-d11
DMT-dT Phosphoramidite-d₁₁ is deuterium labeled DMT-dT Phosphoramidite (HY-W013068). DMT-dT Phosphoramidite is typically used in the synthesis of DNA.

HY-W013068S2

DMT-dT Phosphoramidite-13C
DMT-dT Phosphoramidite- ¹³C is ¹³C-labeled DMT-dT Phosphoramidite (HY-W013068). DMT-dT Phosphoramidite is typically used in the synthesis of DNA.

HY-90006S2

5-Fluorouracil-15N2
5-Fluorouracil- ¹⁵N₂ is the ¹⁵N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .

HY-W013059S2

DMT-dA(bz) Phosphoramidite-d9
DMT-dA(bz) Phosphoramidite-d₉ (DA-CE phosphoramidite-d₉) is deuterium labeled DMT-dA(bz) Phosphoramidite (HY-W013059). DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA.

HY-90006S3

5-Fluorouracil-13C4,15N2

5-Fluorouracil- ¹³C₄, ¹⁵N₂ is the ¹³C and ¹⁵N labeled 5-Fluorouracil . 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .

HY-90006S1

5-Fluorouracil-13C,15N2
5-Fluorouracil- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled 5-Fluorouracil . 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .

HY-101400S

Deoxycytidine triphosphate-d14 dilithium
Deoxycytidine triphosphate-d₁₄ (dCTP-d₁₄ dilithium; 2′-Deoxycytidine-5′-triphosphate-d₁₄) dilithium is deuterium labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-101400S4

Deoxycytidine triphosphate-13C9 dilithium
Deoxycytidine triphosphate- ¹³C₉ (dCTP- ¹³C₉ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹³C₉) dilithium is ¹³C-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-101400S3

Deoxycytidine triphosphate-15N3 dilithium
Deoxycytidine triphosphate- ¹⁵N₃ (dCTP- ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹⁵N₃) dilithium is ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-W048482S4

rU Phosphoramidite-15N
rU Phosphoramidite- ¹⁵N (DMT-2'O-TBDMS-rU phosphoramidite- ¹⁵N) is ¹⁵N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-101400S2

Deoxycytidine triphosphate-13C9,15N3 dilithium

Deoxycytidine triphosphate- ¹³C₉, ¹⁵N₃ (dCTP- ¹³C₉, ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-W048482S3

rU Phosphoramidite-15N2
rU Phosphoramidite- ¹⁵N₂ (DMT-2'O-TBDMS-rU phosphoramidite- ¹⁵N₂) is ¹⁵N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-W048482S2

rU Phosphoramidite-13C9
rU Phosphoramidite- ¹³C₉ (DMT-2'O-TBDMS-rU phosphoramidite- ¹³C₉) is ¹³C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-101400S1

Deoxycytidine triphosphate-15N3,d14 dilithium

Deoxycytidine triphosphate- ¹⁵N₃,d₁₄ (dCTP- ¹⁵N₃,d₁₄ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹⁵N₃,d₁₄) dilithium is deuterium and ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-10820S

Pemetrexed-d5
Pemetrexed-d₅ is the deuterium labeled Pemetrexed . Pemetrexed (LY231514) is an antifolate, the K_i values of the pentaglutamate of Pemetrexed (LY231514) are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively .

HY-138615S1

Deoxythymidine-5'-triphosphate-15N2 dilithium
Deoxythymidine-5'-triphosphate- ¹⁵N₂ (dTTP- ¹⁵N₂) dilithium is ¹⁵N labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.

HY-W048482S1

rU Phosphoramidite-13C9,15N2
rU Phosphoramidite- ¹³C₉, ¹⁵N₂ (DMT-2'O-TBDMS-rU phosphoramidite- ¹³C₉, ¹⁵N₂) is ¹³C and ¹⁵N-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-138615S2

Deoxythymidine-5'-triphosphate-13C10 dilithium
Deoxythymidine-5'-triphosphate- ¹³C₁₀ (dTTP- ¹³C₁₀) dilithium is ¹³C-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.

HY-W048482S

rU Phosphoramidite-13C2,d1
rU Phosphoramidite- ¹³C₂,d₁ (DMT-2'O-TBDMS-rU phosphoramidite- ¹³C₂,d₁) is deuterium and ¹³C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-10820AS

Pemetrexed-d5 disodium
Pemetrexed-d₅ disodium is the deuterium labeled Pemetrexed disodium. Pemetrexed disodium (LY231514 disodium) is an antifolate, the K_is of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively .

HY-B0512S

Sulfamerazine-d4
Sulfamerazine-d₄ is a deuterium labeled Sulfamerazine. Sulfamerazine, a sulfonamide antibacterial, inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthesizes .

HY-138615S4

Deoxythymidine-5'-triphosphate-13C10,15N2 dilithium
Deoxythymidine-5'-triphosphate- ¹³C₁₀, ¹⁵N₂ (dTTP- ¹³C₁₀, ¹⁵N₂) dilithium is ¹³C and ¹⁵N-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.

HY-138615S3

Deoxythymidine-5'-triphosphate-15N2,d15 dilithium
Deoxythymidine-5'-triphosphate- ¹⁵N₂,d₁₅ (dTTP- ¹⁵N₂,d₁₅) dilithium is deuterium and ¹⁵N labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.

HY-W011834S

2'-O-Methylcytidine-d3
2'-O-Methylcytidine-d₃ is deuterium labeled 2'-O-Methylcytidine (HY-W011834). 2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.

HY-14519S1

Methotrexate-d3 diammonium

Methotrexate-d₃ diammonium is the deuterium labeled Methotrexate diammonium. Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) .

HY-138616S1

dGTP-d14 dilithium
dGTP-d₁₄ (2'-Deoxyguanosine-5'-triphosphate-d₁₄) dilithium is deuterium labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-138616S3

dGTP-13C10 dilithium
dGTP- ¹³C₁₀ (2'-Deoxyguanosine-5'-triphosphate- ¹³C₁₀) dilithium is ¹³C-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-138616S

dGTP-15N5 dilithium
dGTP- ¹⁵N₅ (2'-Deoxyguanosine-5'-triphosphate- ¹⁵N₅) dilithium is ¹⁵N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-138616S4

dGTP-13C10,15N5 dilithium

dGTP- ¹³C₁₀, ¹⁵N₅ (2'-Deoxyguanosine-5'-triphosphate- ¹³C₁₀, ¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-138616S2

dGTP-15N5,d14 dilithium

dGTP- ¹⁵N₅,d₁₄ (2'-Deoxyguanosine-5'-triphosphate- ¹⁵N₅,d₁₄) dilithium is deuterium and ¹⁵N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

HY-B0389A

D-Glucose-13C6 Maximum Cited Publications 6 Publications Verification
D-Glucose- ¹³C₆ is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- ¹³C₆ can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .

HY-16637S1

Folic acid-d4
Folic acid-d₄ is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-W726304

Dimethyldichlorosilane
Dimethyldichlorosilane is useful in the synthesis of silanes and siloxanes .

HY-16637S3

Folic acid-13C5
Folic acid- ¹³C₅ is the ¹³C-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-W020033S

Lanosterol-d6
Lanosterol-d₆ is deuterium labeled Lanosterol. Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol s

HY-W010382S

Oxaloacetic acid-13C4
Oxaloacetic acid- ¹³C₄ is the ¹³C-labeled Oxaloacetic acid. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis .

HY-16637S

Folic acid-d2
Folic acid-d₂ (Vitamin B9-d₂) is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-16637S2

(Rac)-Folic acid-13C5,15N
(Rac)-Folic acid- ¹³C₅, ¹⁵N is the ¹³C-labeled and ¹⁵N-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-B0671S

Vancomycin-d12 TFA
Vancomycin-d₁₂ TFA is a deuterium labeled Vancomycin (HY-B0671). Vancomycin is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis .

HY-130569S1

7-Hydroxymethotrexate-d3
7-Hydroxymethotrexate-d₃ is the deuterium labeled 7-Hydroxymethotrexate. 7-Hydroxymethotrexate is a major metabolite of Methotrexate (MTX; HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis[1][2].

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks