2. Others Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Apoptosis NF-κB Immunology/Inflammation
  3. Reference Standards LXR Apoptosis Fatty Acid Synthase (FASN) Reactive Oxygen Species (ROS)
  4. Yamogenin (Standard)

Yamogenin (Standard)  (Synonyms: Neodiosgenin (Standard))

Cat. No.: HY-N2078R
Handling Instructions Technical Support

Yamogenin (Standard) is the analytical standard of Yamogenin. This product is intended for research and analytical applications. Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes. Yamogenin is a steroidal saponin that can be obtained from plant species with in vitro cytotoxicity, antioxidant, and antimicrobial properties. Yamogenin induces cell death via the extrinsic and intrinsic way of apoptosis. Yamogenin inhibits protein denaturation with an IC50 of 1421.92 μg/mL. Yamogenin can be studied in research on gastric cancer.

For research use only. We do not sell to patients.

Yamogenin (Standard)

Yamogenin (Standard) Chemical Structure

CAS No. : 512-06-1

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Yamogenin (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Yamogenin (Standard)512-06-1Neodiosgenin (Standard)Reference StandardsLXRApoptosisFatty Acid Synthase (FASN)Reactive Oxygen Species (ROS)Liver X receptorDiastereomerTGtriacylglyceridefatty acid synthesisInhibitorinhibitorinhibit

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