Pyrimidine-5-boronic acid pinacol ester

Cat. No.: HY-42045 Purity: ≥98.0%: Data Sheet
COA

SDS
Handling Instructions
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Pyrimidine-5-boronic acid pinacol ester is a derivative of Boronic acid. Boronic acid is an intermediate commonly used in organic synthesis reactions and can be used as a key reagent in the Suzuki-Miyaura reaction. It generates organic free radicals through oxygen-mediated oxidation and exhibits potential mutagenic activity. Boronic acid is mainly used in research in the fields of drug synthesis and catalytic reactions. At the same time, it should be noted that it may be a genotoxic impurity (GTIs).

For research use only. We do not sell to patients.

Pyrimidine-5-boronic acid pinacol ester Chemical Structure

CAS No. : 321724-19-0

Size	Stock	Quantity
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

206.05

Formula

C₁₀H₁₅BN₂O₂

CAS No.

321724-19-0

Appearance

Solid

Color

White to off-white

SMILES

CC1(C)OB(C2=CN=CN=C2)OC1(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (485.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8531 mL	24.2655 mL	48.5310 mL
5 mM	0.9706 mL	4.8531 mL	9.7062 mL
10 mM	0.4853 mL	2.4265 mL	4.8531 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

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Data Sheet (274 KB) SDS (393 KB)

COA (253 KB) HNMR (93 KB)

Handling Instructions (2659 KB)

References

[1]. Hansen M M, et al. Boronic Acids and Derivatives Probing the Structure-Activity Relationships for Mutagenicity[J]. Organic Process Research & Development, 2015, 19(11): 1507-1516.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.8531 mL	24.2655 mL	48.5310 mL	121.3274 mL
	5 mM	0.9706 mL	4.8531 mL	9.7062 mL	24.2655 mL
	10 mM	0.4853 mL	2.4265 mL	4.8531 mL	12.1327 mL
	15 mM	0.3235 mL	1.6177 mL	3.2354 mL	8.0885 mL
	20 mM	0.2427 mL	1.2133 mL	2.4265 mL	6.0664 mL
	25 mM	0.1941 mL	0.9706 mL	1.9412 mL	4.8531 mL
	30 mM	0.1618 mL	0.8088 mL	1.6177 mL	4.0442 mL
	40 mM	0.1213 mL	0.6066 mL	1.2133 mL	3.0332 mL
	50 mM	0.0971 mL	0.4853 mL	0.9706 mL	2.4265 mL
	60 mM	0.0809 mL	0.4044 mL	0.8088 mL	2.0221 mL
	80 mM	0.0607 mL	0.3033 mL	0.6066 mL	1.5166 mL
	100 mM	0.0485 mL	0.2427 mL	0.4853 mL	1.2133 mL