3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium

Cat. No.: HY-131799A: Data Sheet Handling Instructions
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3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium is an amine-modified nucleotide that can be used in the synthesis of other active compounds. The coumarin-labeled derivatives of 3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium exhibit significant fluorescence changes when interacting with myosin and can mimic the function of natural ADP.

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3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium Chemical Structure

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Description	3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium is an amine-modified nucleotide that can be used in the synthesis of other active compounds. The coumarin-labeled derivatives of 3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium exhibit significant fluorescence changes when interacting with myosin and can mimic the function of natural ADP^[1]^[2].
Molecular Weight	492.16
Formula	C₁₀H₁₃N₆Na₃O₉P₂
SMILES	O[C@@H]1[C@H](N)[C@@H](COP(OP(O[Na])(O[Na])=O)(O[Na])=O)O[C@H]1N2C3=NC=NC(N)=C3N=C2
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (278 KB) Handling Instructions (2659 KB)
References	[1]. Mojr V, et al. Nonhydrolysable Analogues of (p)ppGpp and (p)ppApp Alarmone Nucleotides as Novel Molecular Tools. ACS Chem Biol. 2021 Sep 17;16(9):1680-1691. [Content Brief] [2]. Webb MR, et al. A series of related nucleotide analogues that aids optimization of fluorescence signals in probing the mechanism of P-loop ATPases, such as actomyosin. Biochemistry. 2004 Nov 16;43(45):14463-71. [Content Brief]