1-Bromo-3-iodobenzene

Name: 1-Bromo-3-iodobenzene
Brand: MedChemExpress
SKU: HY-32149
Rating: 4.5 (1 reviews)

Cat. No.: HY-32149 Purity: 99.99%: Data Sheet
COA

SDS
Handling Instructions
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1-Bromo-3-iodobenzene is a biochemical reagent and an important organic synthetic intermediate. 1-Bromo-3-iodobenzene can be used for the synthesis of other active compounds.

For research use only. We do not sell to patients.

1-Bromo-3-iodobenzene Chemical Structure

CAS No. : 591-18-4

Size	Stock	Quantity
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
250 g	In-stock	Estimated Time of Arrival: December 31
500 g	In-stock	Estimated Time of Arrival: December 31
1 kg	In-stock	Estimated Time of Arrival: December 31

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 1-Bromo-3-iodobenzene:

1-Bromo-3-iodobenzene-d₄ In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

1-Bromo-3-iodobenzene is a biochemical reagent and an important organic synthetic intermediate. 1-Bromo-3-iodobenzene can be used for the synthesis of other active compounds^[1]^[2].

In Vitro

1-Bromo-3-iodobenzene acts as a dihaloarene substrate in the palladium-catalyzed three-component tandem reaction, enabling the one-pot synthesis of unsymmetrical biaryl thioglycosides with thiosugars and arylboronic acids via the selective formation of S-C and C-C bonds for efficient transformation₂.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

282.91

Formula

C₆H₄BrI

CAS No.

591-18-4

Appearance

Liquid (Density: 2.219 g/cm³)

Color

Colorless to light yellow

SMILES

IC1=CC(Br)=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (353.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5347 mL	17.6735 mL	35.3469 mL
5 mM	0.7069 mL	3.5347 mL	7.0694 mL
10 mM	0.3535 mL	1.7673 mL	3.5347 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.99%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (246 KB) HNMR (110 KB) GC (187 KB)

Handling Instructions (2659 KB)

References

[1]. Diemer, et al. Efficient and Complementary Methods Offering Access to Synthetically Valuable 1, 2‐Dibromobenzenes. 2011: 327-340.

[2]. Benmahdjoub S, et al. One-Pot Assembly of Unsymmetrical Biaryl Thioglycosides through Chemoselective Palladium-Catalyzed Three-Component Tandem Reaction. Org Lett. 2018 Jul 6;20(13):4067-4071. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.5347 mL	17.6735 mL	35.3469 mL	88.3673 mL
	5 mM	0.7069 mL	3.5347 mL	7.0694 mL	17.6735 mL
	10 mM	0.3535 mL	1.7673 mL	3.5347 mL	8.8367 mL
	15 mM	0.2356 mL	1.1782 mL	2.3565 mL	5.8912 mL
	20 mM	0.1767 mL	0.8837 mL	1.7673 mL	4.4184 mL
	25 mM	0.1414 mL	0.7069 mL	1.4139 mL	3.5347 mL
	30 mM	0.1178 mL	0.5891 mL	1.1782 mL	2.9456 mL
	40 mM	0.0884 mL	0.4418 mL	0.8837 mL	2.2092 mL
	50 mM	0.0707 mL	0.3535 mL	0.7069 mL	1.7673 mL
	60 mM	0.0589 mL	0.2946 mL	0.5891 mL	1.4728 mL
	80 mM	0.0442 mL	0.2209 mL	0.4418 mL	1.1046 mL
	100 mM	0.0353 mL	0.1767 mL	0.3535 mL	0.8837 mL