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  4. 2-Amino-4-bromopyridine

2-Amino-4-bromopyridine  (Synonyms: 4-Bromopyridine-2-amine)

Cat. No.: HY-41000 Purity: 99.98%
COA
SDS
Handling Instructions Technical Support

2-Amino-4-bromopyridine (4-Bromopyridine-2-amine) is an important intermediate, which can be used for the synthesis of other active compounds.

For research use only. We do not sell to patients.

2-Amino-4-bromopyridine Chemical Structure

2-Amino-4-bromopyridine Chemical Structure

CAS No. : 84249-14-9

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Based on 1 publication(s) in Google Scholar

2-Amino-4-bromopyridine Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

2-Amino-4-bromopyridine (4-Bromopyridine-2-amine) is an important intermediate, which can be used for the synthesis of other active compounds[1].

In Vitro

2-Amino-4-bromopyridine is an important intermediate for the synthesis of 2-aminopyridine derivatives, and its derivative compounds can inhibit tumor cell proliferation by inducing G1 phase arrest and effectively act on wild-type ALK and drug-resistant mutants[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-Amino-4-bromopyridine Related Antibodies
Molecular Weight

173.01

Formula

C5H5BrN2
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

BrC1=CC(N)=NC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (1155.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.7799 mL 28.8996 mL 57.7991 mL
5 mM 1.1560 mL 5.7799 mL 11.5598 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.98%

SDS (393 KB)

COA (246 KB) HNMR (116 KB) LCMS (199 KB) GC (235 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.7799 mL 28.8996 mL 57.7991 mL 144.4978 mL
5 mM 1.1560 mL 5.7799 mL 11.5598 mL 28.8996 mL
10 mM 0.5780 mL 2.8900 mL 5.7799 mL 14.4498 mL
15 mM 0.3853 mL 1.9266 mL 3.8533 mL 9.6332 mL
20 mM 0.2890 mL 1.4450 mL 2.8900 mL 7.2249 mL
25 mM 0.2312 mL 1.1560 mL 2.3120 mL 5.7799 mL
30 mM 0.1927 mL 0.9633 mL 1.9266 mL 4.8166 mL
40 mM 0.1445 mL 0.7225 mL 1.4450 mL 3.6124 mL
50 mM 0.1156 mL 0.5780 mL 1.1560 mL 2.8900 mL
60 mM 0.0963 mL 0.4817 mL 0.9633 mL 2.4083 mL
80 mM 0.0722 mL 0.3612 mL 0.7225 mL 1.8062 mL
100 mM 0.0578 mL 0.2890 mL 0.5780 mL 1.4450 mL
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2-Amino-4-bromopyridine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Amino-4-bromopyridine84249-14-94-Bromopyridine-2-amineBiochemical Assay ReagentsDrug IntermediateDrug Iintermediatebiochemical reagentbiological materialorganic compoundlife scienceintermediateInhibitorinhibitorinhibit

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