2. Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  3. Endogenous Metabolite PDI
  4. Phenylpyruvic acid sodium

Phenylpyruvic acid sodium  (Synonyms: Sodium phenylpyruvate)

Cat. No.: HY-W016203 Purity: 98.24%
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Phenylpyruvic acid sodium is a endogenous metabolite that participates in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase. Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity.

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Phenylpyruvic acid sodium Chemical Structure

Phenylpyruvic acid sodium Chemical Structure

CAS No. : 114-76-1

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Phenylpyruvic acid sodium Related Antibodies

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Description

Phenylpyruvic acid sodium is a endogenous metabolite that participates in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase. Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity[1][2].

Molecular Weight

186.14

Formula

C9H7NaO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C(CC1=CC=CC=C1)=O)O[Na]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 5.83 mg/mL (31.32 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.3723 mL 26.8615 mL 53.7230 mL
5 mM 1.0745 mL 5.3723 mL 10.7446 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.3723 mL 26.8615 mL 53.7230 mL 134.3075 mL
5 mM 1.0745 mL 5.3723 mL 10.7446 mL 26.8615 mL
10 mM 0.5372 mL 2.6862 mL 5.3723 mL 13.4308 mL
15 mM 0.3582 mL 1.7908 mL 3.5815 mL 8.9538 mL
20 mM 0.2686 mL 1.3431 mL 2.6862 mL 6.7154 mL
25 mM 0.2149 mL 1.0745 mL 2.1489 mL 5.3723 mL
30 mM 0.1791 mL 0.8954 mL 1.7908 mL 4.4769 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Phenylpyruvic acid sodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phenylpyruvic acid114-76-1Sodium phenylpyruvateEndogenous MetabolitePDIProtein Disulfide Isomerasesendogenous metabolite3-phenyllactic acidlactate dehydrogenaseInhibitorinhibitorinhibit

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