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  3. Iomeprol intermediate-1

Iomeprol intermediate-1 (compound 5) is an iodinated polysaccharide compound used in the synthesis of contrast agents. The amino group of Iomeprol intermediate-1 can be coupled to the carboxyl group of the D-glucuronide subunit of non-animal stable hyaluronic acid (NASHA), providing a water-soluble, radiopaque moiety.

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Iomeprol intermediate-1 Chemical Structure

Iomeprol intermediate-1 Chemical Structure

CAS No. : 76801-93-9

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Description

Iomeprol intermediate-1 (compound 5) is an iodinated polysaccharide compound used in the synthesis of contrast agents. The amino group of Iomeprol intermediate-1 can be coupled to the carboxyl group of the D-glucuronide subunit of non-animal stable hyaluronic acid (NASHA), providing a water-soluble, radiopaque moiety[1].

Molecular Weight

705.02

Formula

C14H18I3N3O6

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OCC(O)CNC(C1=C(I)C(C(NCC(O)CO)=O)=C(I)C(N)=C1I)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (70.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4184 mL 7.0920 mL 14.1840 mL
5 mM 0.2837 mL 1.4184 mL 2.8368 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4184 mL 7.0920 mL 14.1840 mL 35.4600 mL
5 mM 0.2837 mL 1.4184 mL 2.8368 mL 7.0920 mL
10 mM 0.1418 mL 0.7092 mL 1.4184 mL 3.5460 mL
15 mM 0.0946 mL 0.4728 mL 0.9456 mL 2.3640 mL
20 mM 0.0709 mL 0.3546 mL 0.7092 mL 1.7730 mL
25 mM 0.0567 mL 0.2837 mL 0.5674 mL 1.4184 mL
30 mM 0.0473 mL 0.2364 mL 0.4728 mL 1.1820 mL
40 mM 0.0355 mL 0.1773 mL 0.3546 mL 0.8865 mL
50 mM 0.0284 mL 0.1418 mL 0.2837 mL 0.7092 mL
60 mM 0.0236 mL 0.1182 mL 0.2364 mL 0.5910 mL
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Iomeprol intermediate-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Iomeprol intermediate-1
Cat. No.:
HY-W097018
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