1. PROTAC Protein Tyrosine Kinase/RTK
  2. Target Protein Ligand-Linker Conjugates c-Met/HGFR
  3. 3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid

3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid 

Cat. No.: HY-176385
Handling Instructions Technical Support

3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid is a target protein ligand-linker conjugate that incorporates a ligand for c-Met (HY-451241) and a PROTAC linker (HY-W442078), which recruits E3 ligases. 3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid can be used in the synthesis of PROTACs, such as SJF-8240 (HY-123961).

For research use only. We do not sell to patients.

3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid

3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid Chemical Structure

CAS No. : 2230826-10-3

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Description

3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid is a target protein ligand-linker conjugate that incorporates a ligand for c-Met (HY-451241) and a PROTAC linker (HY-W442078), which recruits E3 ligases. 3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid can be used in the synthesis of PROTACs, such as SJF-8240 (HY-123961)[1].

Molecular Weight

693.69

Formula

C36H37F2N3O9

CAS No.
SMILES

FC1=CC=C(C=C1)NC(C2(C(NC3=CC(F)=C(C=C3)OC4=CC=NC5=C4C=C(C(OCCCOCCCOCCC(O)=O)=C5)OC)=O)CC2)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid
Cat. No.:
HY-176385
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