2-Heptyl-4-quinolone

Cat. No.: HY-129503 Purity: 99.06%: Data Sheet
COA

SDS
Handling Instructions
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2-Heptyl-4-quinolone is an intermediate in the synthesis of the Pseudomonas quinolone signal (PQS) that controls swarming by positively regulating phenazine production. 2-Heptyl-4-quinolone induces the production of the phenazine-1-carboxylic acid (PCA).

For research use only. We do not sell to patients.

2-Heptyl-4-quinolone Chemical Structure

CAS No. : 40522-46-1

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of 2-Heptyl-4-quinolone:

2-Heptyl-4-quinolone-¹³C₆ Get quote
2-Heptyl-4-quinolone-¹⁵N Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Cellular Effect

Cell Line	Type	Value	Description	References
A2780	IC₅₀	35 μM Compound: 1	Antiproliferative activity against human A2780 cells after 2 days by Alamar blue assay Antiproliferative activity against human A2780 cells after 2 days by Alamar blue assay	[PMID: 28648491]

Molecular Weight

243.34

Formula

C₁₆H₂₁NO

CAS No.

40522-46-1

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C=C(CCCCCCC)NC2=C1C=CC=C2

Structure Classification

Initial Source

Microorganisms

Pseudomonas aeruginosa

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

RT, protect from light

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (205.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.1095 mL	20.5474 mL	41.0948 mL
5 mM	0.8219 mL	4.1095 mL	8.2190 mL
10 mM	0.4109 mL	2.0547 mL	4.1095 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.06%

Select Batch:

Data Sheet (266 KB) SDS (392 KB)

COA (242 KB) HNMR (272 KB) LCMS (92 KB)

Handling Instructions (2659 KB)

References

[1]. Ha DG, et al. 2-Heptyl-4-quinolone, a precursor of the Pseudomonas quinolone signal molecule, modulates swarming motility in Pseudomonas aeruginosa. J Bacteriol. 2011 Dec;193(23):6770-80. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.1095 mL	20.5474 mL	41.0948 mL	102.7369 mL
	5 mM	0.8219 mL	4.1095 mL	8.2190 mL	20.5474 mL
	10 mM	0.4109 mL	2.0547 mL	4.1095 mL	10.2737 mL
	15 mM	0.2740 mL	1.3698 mL	2.7397 mL	6.8491 mL
	20 mM	0.2055 mL	1.0274 mL	2.0547 mL	5.1368 mL
	25 mM	0.1644 mL	0.8219 mL	1.6438 mL	4.1095 mL
	30 mM	0.1370 mL	0.6849 mL	1.3698 mL	3.4246 mL
	40 mM	0.1027 mL	0.5137 mL	1.0274 mL	2.5684 mL
	50 mM	0.0822 mL	0.4109 mL	0.8219 mL	2.0547 mL
	60 mM	0.0685 mL	0.3425 mL	0.6849 mL	1.7123 mL
	80 mM	0.0514 mL	0.2568 mL	0.5137 mL	1.2842 mL
	100 mM	0.0411 mL	0.2055 mL	0.4109 mL	1.0274 mL