2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. Dihydrodeoxyuridine

Dihydrodeoxyuridine  (Synonyms: H2dUrd)

Cat. No.: HY-130806 Purity: 98.71%
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Handling Instructions Technical Support

Dihydrodeoxyuridine (H2dUrd) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

Dihydrodeoxyuridine Chemical Structure

Dihydrodeoxyuridine Chemical Structure

CAS No. : 5626-99-3

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Based on 1 publication(s) in Google Scholar

Dihydrodeoxyuridine Related Antibodies

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Description

Dihydrodeoxyuridine (H2dUrd) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Molecular Weight

230.22

Formula

C9H14N2O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1NC(CCN1[C@H]2C[C@H](O)[C@@H](CO)O2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (542.96 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3437 mL 21.7184 mL 43.4367 mL
5 mM 0.8687 mL 4.3437 mL 8.6873 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.3437 mL 21.7184 mL 43.4367 mL 108.5918 mL
5 mM 0.8687 mL 4.3437 mL 8.6873 mL 21.7184 mL
10 mM 0.4344 mL 2.1718 mL 4.3437 mL 10.8592 mL
15 mM 0.2896 mL 1.4479 mL 2.8958 mL 7.2395 mL
20 mM 0.2172 mL 1.0859 mL 2.1718 mL 5.4296 mL
25 mM 0.1737 mL 0.8687 mL 1.7375 mL 4.3437 mL
30 mM 0.1448 mL 0.7239 mL 1.4479 mL 3.6197 mL
40 mM 0.1086 mL 0.5430 mL 1.0859 mL 2.7148 mL
50 mM 0.0869 mL 0.4344 mL 0.8687 mL 2.1718 mL
60 mM 0.0724 mL 0.3620 mL 0.7239 mL 1.8099 mL
80 mM 0.0543 mL 0.2715 mL 0.5430 mL 1.3574 mL
100 mM 0.0434 mL 0.2172 mL 0.4344 mL 1.0859 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dihydrodeoxyuridine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dihydrodeoxyuridine5626-99-3H2dUrdNucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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