2. Anti-infection
  3. Bacterial Antibiotic
  4. Mafenide

Mafenide is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis.

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Mafenide

Mafenide Chemical Structure

CAS No. : 138-39-6

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Mafenide Related Antibodies

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Description

Mafenide is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis[1][2].

Clinical Trial
Molecular Weight

186.23

Formula

C7H10N2O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC=C(CN)C=C1)(N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 30.3 mg/mL (162.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.3697 mL 26.8485 mL 53.6970 mL
5 mM 1.0739 mL 5.3697 mL 10.7394 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.3697 mL 26.8485 mL 53.6970 mL 134.2426 mL
5 mM 1.0739 mL 5.3697 mL 10.7394 mL 26.8485 mL
10 mM 0.5370 mL 2.6849 mL 5.3697 mL 13.4243 mL
15 mM 0.3580 mL 1.7899 mL 3.5798 mL 8.9495 mL
20 mM 0.2685 mL 1.3424 mL 2.6849 mL 6.7121 mL
25 mM 0.2148 mL 1.0739 mL 2.1479 mL 5.3697 mL
30 mM 0.1790 mL 0.8950 mL 1.7899 mL 4.4748 mL
40 mM 0.1342 mL 0.6712 mL 1.3424 mL 3.3561 mL
50 mM 0.1074 mL 0.5370 mL 1.0739 mL 2.6849 mL
60 mM 0.0895 mL 0.4475 mL 0.8950 mL 2.2374 mL
80 mM 0.0671 mL 0.3356 mL 0.6712 mL 1.6780 mL
100 mM 0.0537 mL 0.2685 mL 0.5370 mL 1.3424 mL
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Mafenide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mafenide138-39-6BacterialAntibioticInhibitorinhibitorinhibit

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