2. PROTAC
  3. Ligands for Target Protein for PROTAC
  4. Smurf1 ligand 1

Smurf1 ligand 1 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). Smurf1 ligand 1 can be used for synthesis SMART1 (HY-W998345).

For research use only. We do not sell to patients.

Smurf1 ligand 1

Smurf1 ligand 1 Chemical Structure

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Smurf1 ligand 1 Related Antibodies

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Description

Smurf1 ligand 1 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). Smurf1 ligand 1 can be used for synthesis SMART1 (HY-W998345)[1].

Molecular Weight

386.41

Formula

C21H18N6O2
Appearance

Solid

Color

Light brown to brown

SMILES

CNC(C1=NC=CC(OC2=CC=C(C=C2)N3C=C(N=N3)C4=CC(N)=CC=C4)=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 17.5 mg/mL (45.29 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5879 mL 12.9396 mL 25.8792 mL
5 mM 0.5176 mL 2.5879 mL 5.1758 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5879 mL 12.9396 mL 25.8792 mL 64.6981 mL
5 mM 0.5176 mL 2.5879 mL 5.1758 mL 12.9396 mL
10 mM 0.2588 mL 1.2940 mL 2.5879 mL 6.4698 mL
15 mM 0.1725 mL 0.8626 mL 1.7253 mL 4.3132 mL
20 mM 0.1294 mL 0.6470 mL 1.2940 mL 3.2349 mL
25 mM 0.1035 mL 0.5176 mL 1.0352 mL 2.5879 mL
30 mM 0.0863 mL 0.4313 mL 0.8626 mL 2.1566 mL
40 mM 0.0647 mL 0.3235 mL 0.6470 mL 1.6175 mL
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Smurf1 ligand 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Smurf1 ligand 1Ligands for Target Protein for PROTACTarget Protein-binding MoietyInhibitorinhibitorinhibit

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