Amino-PEG4-GGFG-Dxd

Cat. No.: HY-158768 Purity: 99.95%: Data Sheet
COA

SDS
Handling Instructions
FAQs
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Amino-PEG4-GGFG-Dxd (Compound 13-7) is a drug-linker conjugate for ADC. Amino-PEG4-GGFG-Dxd is composed of Dxd (HY-13631D) and a linker. Amino-PEG4-GGFG-Dxd can be used for synthesis of ADCs

For research use only. We do not sell to patients.

Amino-PEG4-GGFG-Dxd Chemical Structure

CAS No. : 2879227-88-8

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	Get quote
50 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Amino-PEG4-GGFG-Dxd (Compound 13-7) is a drug-linker conjugate for ADC. Amino-PEG4-GGFG-Dxd is composed of Dxd (HY-13631D) and a linker. Amino-PEG4-GGFG-Dxd can be used for synthesis of ADCs^[1]

Molecular Weight

1088.14

Formula

C₅₃H₆₆FN₉O₁₅

CAS No.

2879227-88-8

Appearance

Solid

Color

Off-white to light yellow

SMILES

NCCOCCOCCOCCOCCC(NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(NCOCC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (91.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.9190 mL	4.5950 mL	9.1900 mL
5 mM	0.1838 mL	0.9190 mL	1.8380 mL
10 mM	0.0919 mL	0.4595 mL	0.9190 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.95%

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Data Sheet (268 KB) SDS (252 KB)

COA (251 KB) HNMR (427 KB) RP-HPLC (206 KB) LCMS (104 KB)

Handling Instructions (2659 KB)

References

[1]. Tian Qiang, et al. Chemical coupling linker and use thereof. Patent. WO2022253033

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.9190 mL	4.5950 mL	9.1900 mL	22.9750 mL
	5 mM	0.1838 mL	0.9190 mL	1.8380 mL	4.5950 mL
	10 mM	0.0919 mL	0.4595 mL	0.9190 mL	2.2975 mL
	15 mM	0.0613 mL	0.3063 mL	0.6127 mL	1.5317 mL
	20 mM	0.0459 mL	0.2297 mL	0.4595 mL	1.1487 mL
	25 mM	0.0368 mL	0.1838 mL	0.3676 mL	0.9190 mL
	30 mM	0.0306 mL	0.1532 mL	0.3063 mL	0.7658 mL
	40 mM	0.0230 mL	0.1149 mL	0.2297 mL	0.5744 mL
	50 mM	0.0184 mL	0.0919 mL	0.1838 mL	0.4595 mL
	60 mM	0.0153 mL	0.0766 mL	0.1532 mL	0.3829 mL
	80 mM	0.0115 mL	0.0574 mL	0.1149 mL	0.2872 mL