Aminopotentidine

Cat. No.: HY-101167 Purity: 98.54%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

Aminopotentidine is a histamine H2 receptor antagonist with K_B values of 220 nM and 280 nM for human and guinea pig H2 receptors, respectively. It can also serve as a precursor for the synthesis of [125I] iodo derivatives.

For research use only. We do not sell to patients.

Aminopotentidine Chemical Structure

CAS No. : 140873-26-3

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

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H₁ Receptor H₂ Receptor H₃ Receptor H₄ Receptor Histamine Receptor

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

H₂ Receptor

220 nM (Kb)

Molecular Weight

477.60

Formula

C₂₆H₃₅N₇O₂

CAS No.

140873-26-3

Appearance

Solid

Color

White to off-white

SMILES

O=C(NCCN/C(NC#N)=N/CCCOC1=CC=CC(CN2CCCCC2)=C1)C3=CC=C(N)C=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (104.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0938 mL	10.4690 mL	20.9380 mL
5 mM	0.4188 mL	2.0938 mL	4.1876 mL
10 mM	0.2094 mL	1.0469 mL	2.0938 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.54%

Select Batch:

Data Sheet (266 KB) SDS (251 KB)

COA (242 KB) HNMR (270 KB) LCMS (97 KB)

Handling Instructions (2659 KB)

References

[1]. Hirschfeld J, et al. Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H2 receptor[J]. Journal of medicinal chemistry, 1992, 35(12): 2231-2238. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0938 mL	10.4690 mL	20.9380 mL	52.3451 mL
	5 mM	0.4188 mL	2.0938 mL	4.1876 mL	10.4690 mL
	10 mM	0.2094 mL	1.0469 mL	2.0938 mL	5.2345 mL
	15 mM	0.1396 mL	0.6979 mL	1.3959 mL	3.4897 mL
	20 mM	0.1047 mL	0.5235 mL	1.0469 mL	2.6173 mL
	25 mM	0.0838 mL	0.4188 mL	0.8375 mL	2.0938 mL
	30 mM	0.0698 mL	0.3490 mL	0.6979 mL	1.7448 mL
	40 mM	0.0523 mL	0.2617 mL	0.5235 mL	1.3086 mL
	50 mM	0.0419 mL	0.2094 mL	0.4188 mL	1.0469 mL
	60 mM	0.0349 mL	0.1745 mL	0.3490 mL	0.8724 mL
	80 mM	0.0262 mL	0.1309 mL	0.2617 mL	0.6543 mL
	100 mM	0.0209 mL	0.1047 mL	0.2094 mL	0.5235 mL