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  3. Biochemical Assay Reagents
  4. HOAT

HOAT is a commonly used peptide bond forming agent that may become an impurity in drug synthesis, but is not mutagenic. HOAT can be used for peptide fragment polycondensation and can also inhibit the racemization of peptide polycondensation.

For research use only. We do not sell to patients.

HOAT Chemical Structure

HOAT Chemical Structure

CAS No. : 39968-33-7

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HOAT Related Antibodies

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Description

HOAT is a commonly used peptide bond forming agent that may become an impurity in drug synthesis, but is not mutagenic. HOAT can be used for peptide fragment polycondensation and can also inhibit the racemization of peptide polycondensation[1].

Molecular Weight

136.11

Formula

C5H4N4O
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

ON1C2=NC=CC=C2N=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (1469.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.3470 mL 36.7350 mL 73.4700 mL
5 mM 1.4694 mL 7.3470 mL 14.6940 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.98%

SDS (604 KB)

COA (254 KB) HNMR (121 KB) RP-HPLC (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.3470 mL 36.7350 mL 73.4700 mL 183.6750 mL
5 mM 1.4694 mL 7.3470 mL 14.6940 mL 36.7350 mL
10 mM 0.7347 mL 3.6735 mL 7.3470 mL 18.3675 mL
15 mM 0.4898 mL 2.4490 mL 4.8980 mL 12.2450 mL
20 mM 0.3673 mL 1.8367 mL 3.6735 mL 9.1837 mL
25 mM 0.2939 mL 1.4694 mL 2.9388 mL 7.3470 mL
30 mM 0.2449 mL 1.2245 mL 2.4490 mL 6.1225 mL
40 mM 0.1837 mL 0.9184 mL 1.8367 mL 4.5919 mL
50 mM 0.1469 mL 0.7347 mL 1.4694 mL 3.6735 mL
60 mM 0.1224 mL 0.6122 mL 1.2245 mL 3.0612 mL
80 mM 0.0918 mL 0.4592 mL 0.9184 mL 2.2959 mL
100 mM 0.0735 mL 0.3673 mL 0.7347 mL 1.8367 mL
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HOAT Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HOAT39968-33-7Biochemical Assay ReagentsInhibitorinhibitorinhibit

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