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  3. Exatecan intermediate 12-d5

Exatecan intermediate 12-d5 is the deuterium labeled Exatecan intermediate 12 (HY-45171). Exatecan intermediate 12 is an intermediate for the synthesis of ADC toxin Exatecan (HY-13631) and can be used to prepare ADC compounds.

For research use only. We do not sell to patients.

Exatecan intermediate 12-d<sub>5</sub> Chemical Structure

Exatecan intermediate 12-d5 Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Description

Exatecan intermediate 12-d5 is the deuterium labeled Exatecan intermediate 12 (HY-45171). Exatecan intermediate 12 is an intermediate for the synthesis of ADC toxin Exatecan (HY-13631) and can be used to prepare ADC compounds.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

312.33

Formula

C15H12D5NO6

Unlabeled CAS
SMILES

O=C1N2C(C3(CC2)OCCO3)=CC([C@@](C([2H])(C([2H])([2H])[2H])[2H])4O)=C1COC4=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Exatecan intermediate 12-d5
Cat. No.:
HY-45171S
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