2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Maleimide-PEG2-hydrazide TFA

Maleimide-PEG2-hydrazide (TFA) is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Maleimide-PEG2-hydrazide TFA Chemical Structure

Maleimide-PEG2-hydrazide TFA Chemical Structure

CAS No. : 2512213-64-6

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Maleimide-PEG2-hydrazide TFA Related Antibodies

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Description

Maleimide-PEG2-hydrazide (TFA) is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Acid Cleavable Linker

 

Cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Maleimide-PEG2-hydrazide TFA Related Antibodies
Molecular Weight

456.37

Formula

C16H23F3N4O8
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

NNC(CCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O.O=C(O)C(F)(F)F
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Maleimide-PEG2-hydrazide TFA Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Maleimide-PEG2-hydrazide2512213-64-6ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product Name:
Maleimide-PEG2-hydrazide TFA
Cat. No.:
HY-136097
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