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  3. 6-Bromonicotinic acid

6-Bromonicotinic acid is a brominated derivative of Niacin (HY-B0143), can be used as a drug intermediate for the synthesis of Anabaseine (HY-115766) derivatives.

For research use only. We do not sell to patients.

6-Bromonicotinic acid

6-Bromonicotinic acid Chemical Structure

CAS No. : 6311-35-9

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Based on 1 publication(s) in Google Scholar

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Description

6-Bromonicotinic acid is a brominated derivative of Niacin (HY-B0143), can be used as a drug intermediate for the synthesis of Anabaseine (HY-115766) derivatives.

Molecular Weight

202.01

Formula

C6H4BrNO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

BrC1=NC=C(C(O)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (990.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9503 mL 24.7516 mL 49.5032 mL
5 mM 0.9901 mL 4.9503 mL 9.9006 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.75%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.9503 mL 24.7516 mL 49.5032 mL 123.7581 mL
5 mM 0.9901 mL 4.9503 mL 9.9006 mL 24.7516 mL
10 mM 0.4950 mL 2.4752 mL 4.9503 mL 12.3758 mL
15 mM 0.3300 mL 1.6501 mL 3.3002 mL 8.2505 mL
20 mM 0.2475 mL 1.2376 mL 2.4752 mL 6.1879 mL
25 mM 0.1980 mL 0.9901 mL 1.9801 mL 4.9503 mL
30 mM 0.1650 mL 0.8251 mL 1.6501 mL 4.1253 mL
40 mM 0.1238 mL 0.6188 mL 1.2376 mL 3.0940 mL
50 mM 0.0990 mL 0.4950 mL 0.9901 mL 2.4752 mL
60 mM 0.0825 mL 0.4125 mL 0.8251 mL 2.0626 mL
80 mM 0.0619 mL 0.3094 mL 0.6188 mL 1.5470 mL
100 mM 0.0495 mL 0.2475 mL 0.4950 mL 1.2376 mL
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6-Bromonicotinic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
6-Bromonicotinic acid
Cat. No.:
HY-W002864
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